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Dr. Sylaja P. N.

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Contact Information

Address:

Dr. Sylaja P. N.
Professor
Neurology Department

Phone number:

4482(O), 2452287 (R)

People - Neurology Department

Dr. Sylaja P. N.

Academic Qualifications

  • MBBS ;Trivandrum Medical College;1986
  • MD (Medicine);Trivandrum Medical College;1993
  • DM (Neurology);SCTIMST;1998

Professional Record

  • Additional Professor ,Dept of Neurology;SCTIMST;since July 2010
  • Assistant Professor of Neurology;SCTIMST;Feb 1999-June 2005
  • Senior consultant neurologist;Ananthapuri Hospitals ;Jan 2007-June2010

Awards

  • Young scientist award 2008- Physicians association of Trivandrum
  • Best paper award at Annual conference of Neurological Society of India in 2002

Area of Interest

  • Stroke and Epilepsy

Current Activities

  • in charge of Comprehensive stroke program

Fellowships

  • Fellowship of Cerebrovascular diseases ,at University of Calgary, Canada( July2005-Nov 2006)

Membership

  • Indian Epilepsy Association (life member)
  • Neurological Society of India (life member)
  • Indian Medical Association (life member)
  • Indian Epilepsy Society (life member)
  • Indian Academy of Neurology (life member)
  • World Stroke Organization
  • Indian Stroke Association (life member)

On-going Projects

  • A Phase IIb prospective, randomized, double-blind, multi-center, dose escalation placebo controlled study of NTx-265: human chorionic gonadotropin (hCG) and epoetin alfa (EPO) in acute ischemic stroke patients (REGENESIS) Principal investigator-Dr.P.N.Sylaja Status: Completed Sponsor: Stem cell Therapeutics Corporation,Canada.
  • Conducted a study on the Impact of nutrition on the outcome of stroke in collaboration with CMC Ludhiana.
  • Ongoing multicentric study on risk stratification in patients with TIA and minor strokes

Publications

Article

  1. Coutts, S B; Sylaja, P N; Choi, Y B; Al-Khathami, A; Sivakumar, C; Jeerakathil, T J; Sarma, P S; Hill, M D, The ASPIRE Approach for TIA Risk Stratification., Can J Neurol Sci, 2011, 38; 78-81, http://www.ncbi.nlm.nih.gov/pubmed/21156434
  2. Shobha, N; Sylaja, P N; Kapral, M K; Fang, J; Hill, M D; Investigators of the Registry of the Canadian Stroke Network, Differences in stroke outcome based on sex., Neurology, 2010, 74; 767---71, http://www.ncbi.nlm.nih.gov/pubmed/20194917
  3. Sridharan, Sapna E; Unnikrishnan, J P; Sukumaran, Sajith; Sylaja, P N; Nayak, S Dinesh; Sarma, P Sankara; Radhakrishnan, Kurupath, Incidence, types, risk factors, and outcome of stroke in a developing country: the Trivandrum Stroke Registry., Stroke, 2009, 40; 1212---8, http://www.ncbi.nlm.nih.gov/pubmed/19228849
  4. Sylaja, P N; Hill, Michael D, Transient ischemic attacksâ--definition, risk prediction and urgent management., Neurol India, 2009, 57; 252---6, http://www.ncbi.nlm.nih.gov/pubmed/19587463
  5. Puetz, V; Sylaja, P N; Hill, M D; Coutts, S B; Dzialowski, I; Becker, U; Gahn, G; von Kummer, R; Demchuk, A M, CT angiography source images predict final infarct extent in patients with basilar artery occlusion., AJNR Am J Neuroradiol, 2009, 30; 1877---83, http://www.ncbi.nlm.nih.gov/pubmed/19643923
  6. Sylaja, P N; Dzialowski, Imanuel; Puetz, Volker; Eliasziw, Michael; Hill, Michael D; Krol, Andrea; O'Reilly, Christine; Demchuk, Andrew M, Does intravenous rtPA benefit patients in the absence of CT angiographically visible intracranial occlusion?, Neurol India, 2009, 57; 739---43, http://www.ncbi.nlm.nih.gov/pubmed/20139502
  7. Sylaja, P N; Setiawan, Melissa; Hill, Michael D; Demchuk, Andrew M; Wong, John, Treatment of stroke after carotid endarterectomy using intravenous abciximab., Neurol India, 2009, 57; 780---2, http://www.ncbi.nlm.nih.gov/pubmed/20139510
  8. Sylaja, P N; Puetz, Volker; Dzialowski, Imanuel; Krol, Andrea; Hill, Michael D; Demchuk, Andrew M, Prognostic value of CT angiography in patients with suspected vertebrobasilar ischemia., J Neuroimaging, 2008, 18; 46---9, http://www.ncbi.nlm.nih.gov/pubmed/18190495
  9. Sylaja, P N; Coutts, Shelagh B; Krol, Andrea; Hill, Michael D; Demchuk, Andrew M; VISION Study Group, When to expect negative diffusion-weighted images in stroke and transient ischemic attack., Stroke, 2008, 39; 1898---900, http://www.ncbi.nlm.nih.gov/pubmed/18420957
  10. Puetz, Volker; Dzialowski, Imanuel; Hill, Michael D; Subramaniam, Suresh; Sylaja, P N; Krol, Andrea; O'Reilly, Christine; Hudon, Mark E; Hu, William Y; Coutts, Shelagh B; Barber, Philip A; Watson, Tim, Intracranial thrombus extent predicts clinical outcome, final infarct size and hemorrhagic transformation in ischemic stroke: the clot burden score., Int J Stroke, 2008, 3; 230---6, http://www.ncbi.nlm.nih.gov/pubmed/18811738
  11. Puetz, Volker; Sylaja, P N; Coutts, Shelagh B; Hill, Michael D; Dzialowski, Imanuel; Mueller, Pia; Becker, Ulf; Urban, Gabriele; O'Reilly, Christine; Barber, Philip A; Sharma, Pranshu; Goyal, Mayank;, Extent of hypoattenuation on CT angiography source images predicts functional outcome in patients with basilar artery occlusion., Stroke, 2008, 39; 2485---90, http://www.ncbi.nlm.nih.gov/pubmed/18617663
  12. Sylaja, P.; Demchuk, Andrew., Intravenous thrombolytic therapy in acute ischemic stroke: The art and science of treatment decision making, Annals of Indian Academy of Neurology, 2008, 11; 24---29, http://www.annalsofian.org/article.asp?issn=0972-2327;year=2008;volume=11;issue=5;spage=24;epage=29;aulast=Sylaja;t=6
  13. Tÿ©llez-Zenteno, Josÿ© F; Pillai, Sylaja N; Hill, Michael D; Pillay, Neelan, Chronic PLEDs with transitional rhythmic discharges (PLEDs-plus) in remote stroke., Epileptic Disord, 2007, 9; 164---9, http://www.ncbi.nlm.nih.gov/pubmed/17525027
  14. Sylaja, R N; Goyal, M; Watson, T; Hill, M D, Wallerian-like degeneration after ischemic stroke revealed by diffusionâ--weighted imaging., Can J Neurol Sci, 2007, 34; 243---4, http://www.ncbi.nlm.nih.gov/pubmed/17598606
  15. Sylaja, P N; Dong, Wei; Grotta, James C; Miller, Mary K; Tomita, Kristen; Hamilton, Scott; Semba, Charles; Hill, Michael D, Safety outcomes of Alteplase among acute ischemic stroke patients with special characteristics., Neurocrit Care, 2007, 6; 181---5, http://www.ncbi.nlm.nih.gov/pubmed/17572861
  16. Varma, Nisha P; Sylaja, Padmavathy N; George, Lincy; Sankara Sarma, P; Radhakrishnan, Kurupath, Employment concerns of people with epilepsy in Kerala, south India., Epilepsy Behav, 2007, 10; 250---4, http://www.ncbi.nlm.nih.gov/pubmed/17218155
  17. Lipska, K; Sylaja, P N; Sarma, P S; Thankappan, K R; Kutty, V R; Vasan, R S; Radhakrishnan, K, Risk factors for acute ischaemic stroke in young adults in South India., J Neurol Neurosurg Psychiatry, 2007, 78; 959---63, http://www.ncbi.nlm.nih.gov/pubmed/17220290
  18. Durai Pandian, Jeyaraj; Padma, Vasantha; Vijaya, Pamidimukkala; Sylaja, P N; Murthy, Jagaralpudi M K, Stroke and thrombolysis in developing countries., Int J Stroke, 2007, 2; 17---26, http://www.ncbi.nlm.nih.gov/pubmed/18705983
  19. Sylaja, P N; Coutts, S B; Subramaniam, S; Hill, M D; Eliasziw, M; Demchuk, A M; VISION Study Group, Acute ischemic lesions of varying ages predict risk of ischemic events in stroke/TIA patients., Neurology, 2007, 68; 415---9, http://www.ncbi.nlm.nih.gov/pubmed/17283315
  20. Sylaja, P N; Hill, Michael D, Stroke due to calcific embolus following coronary angiography., Neurology, 2006, 67; E16, http://www.ncbi.nlm.nih.gov/pubmed/17101880
  21. Sylaja, P N; Cote, Robert; Buchan, Alastair M; Hill, Michael D; Canadian Alteplase for Stroke Effectiveness Study (CASES) Investigators, Thrombolysis in patients older than 80 years with acute ischaemic stroke: Canadian Alteplase for Stroke Effectiveness Study., J Neurol Neurosurg Psychiatry, 2006, 77; 826---9, http://www.ncbi.nlm.nih.gov/pubmed/16505004
  22. Sylaja, P N; Dzialowski, Imanuel; Krol, Andrea; Roy, Jayanta; Federico, Paolo; Demchuk, Andrew M; Calgary Stroke Program, Role of CT angiography in thrombolysis decision-making for patients with presumed seizure at stroke onset., Stroke, 2006, 37; 915---7, http://www.ncbi.nlm.nih.gov/pubmed/16456124
  23. Sylaja, P N; Radhakrishnan, K; Kesavadas, C; Sarma, P S, Seizure outcome after anterior temporal lobectomy and its predictors in patients with apparent temporal lobe epilepsy and normal MRI., Epilepsia, 2004, 45; 803---8, http://www.ncbi.nlm.nih.gov/pubmed/15230705
  24. Vijai, J; Cherian, P J; Sylaja, P N; Anand, A; Radhakrishnan, K, Clinical characteristics of a South Indian cohort of juvenile myoclonic epilepsy probands., Seizure, 2003, 12; 490---6, http://www.ncbi.nlm.nih.gov/pubmed/12967578
  25. Sylaja, P N; Ahsan Moosa, N V; Radhakrishnan, K; Sankara Sarma, P; Pradeep Kumar, S, Differential diagnosis of patients with intracranial sinus venous thrombosis related isolated intracranial hypertension from those with idiopathic intracranial hypertension., J Neurol Sci, 2003, 215; 9---12, http://www.ncbi.nlm.nih.gov/pubmed/14568121
  26. Sylaja, P.N.; Radhakrishnan, K., Problems and pitfalls in developing countries, Epilepsia, 2003, 44; 48---50, http://onlinelibrary.wiley.com/doi/10.1046/j.1528-1157.44.s.1.11.x/full