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Dr. Ramesh P.

Ramesh P

Contact Information

Address:

Dr. Ramesh P.
Scientist 'G' (Senior Grade) & Scientist-in-Charge [Joint]
Division of Polymeric Medical Devices

Phone number:

1225(O), 0471-2343752 (R)

People - Division of Polymeric Medical Devices

Dr. Ramesh P.

Academic Qualifications

  • Ph.D., IIT, Kharagpur, West Bengal, 1993.
  • M.Tech, Polymer Technology, Cochin University of Science and Technology, Kochi,1989.
  • B.Tech, Polymer Science and Rubber Technology, Cochin University of Science and Technology, Kochi, 1987.

Professional Record

  • Scientist G & joint-in-charge. Division of Polymeric Medical Devices, SCTIMST, Thiruvananthapuram. December 2013 - to date.
  • Quality Manager, March 2013-February 2023
  • Scientist F & joint-in-charge, Polymer Processing Laboratory & Deputy Quality Manager, SCTIMST, Thiruvananthapuram. December 2009 - December 2013.
  • Scientist at SCTIMST, Thiruvananthapuram. December 1993 - December 2009.
  • Research Associate (CSIR) at Rubber Technology Centre, Indian Institute of Technology, Kharagpur, October 1992 - December 1993.

Honors

  • University First Rank with First Class & Honours for B.Tech.
  • University First Rank with First Class for M.Tech.

Area of Interest

  • Biomedical applications of polymers.
  • Polymer blends & composites,Nanocomposites.
  • Electrospinning of polymers and composites.
  • Non-toxic natural rubber latex products, Conductive composites for bio-electrodes.

Current Activities

  • Electrospinning of polymers and composites, degradable composites, electrically conductive composites, non-toxic natural rubber latex products.

Patents

  • 'A process for preparing rubber articles of low friction coefficient' Roy Joseph, P.Ramesh and R.Sivakumar.
  • 'Spray dried hydroxyapatite microspheres and a class of microstructured microspheres for biomedical applications', H.K.Varma, P.Ramesh, M.C.Sunny & S. Suresh Babu.
  • 'Dense and porous ceramic microspheres by a novel stirring method', H.K.Varma, S. Suresh Babu, M.C.Sunny & P.Ramesh.
  • 'Osteoconductive bioceramic filled polymer composites for use as bone substitute' P.Ramesh and H.K.Varma.

Fellowships

  • Visiting Scientist, Institute for Composite Materials, University of Kaiserslautern, Germany, July-August 2001 & November 2003.

Membership

  • Member - Society for Polymer Science India, Materials Research Society of India, Society for Biomaterials & Artificial Organs.

On-going Projects

  • 'Combination product of polymer-ceramic composites with cells and growth factors for bone tissue engineering applications', (Funded by Dept. of Biotechnology) (Principal Investigator).
  • 'Development of a Dura Substitute by Electrospinning of e-Caprolactone-co-Lactide Polymers' (Funded by KSCSTEC), (Principal Investigator).
  • 'Implanted Neural Interfaces and Control Schemes for Artificial Hand Control' (Funded by Dept. of Biotechnology), in collaboration with CMC, Vellore. (Co-investigator).
  • 'Development and Evaluation of a drug releasing intra-uterine system', (Funded by HLL Lifecare Ltd., Trivandrum), January 2007- Dec.2010 (Co-investigator).

Team

  • Mr. Sooraj M.R., Ph.D. student
  • Ms.Jasmin Joseph, Scientific Assistant
  • Ms.Prathyusha, Ph.D. student.
  • Ms.Theerdha V. Nair, Ph.D. student.
  • Ms. Athira M., Ph.D. student

No. of Publications

  • Medha Surendranath, Rekha M R, Prakash Nair and P. Ramesh, ‘Electrospun Mucoadhesive Zein/PVP Fibroporous Membrane for Transepithelial Delivery of Propranolol Hydrochloride’, Molecular Pharmaceutics, (I.F.= 5.364) ) https://doi.org/10.1021/acs.molpharmaceut.2c00746
  • S. Prima and P. Ramesh, ’Neuronal cell response on aligned fibroporous electrospun mat generated from silver ion complexed ethylene vinyl alcohol copolymer’, Journal of Biomedical Materials Research- Part B Applied Biomaterials (I.F.=3.405) https://doi.org/10.1002/jbm.b.35189
  • Remya K. Rajan, Sunitha Chandran, Annie John and P. Ramesh (2022): Nanofibrous polycaprolactone-polyethylene glycol-based scaffolds embedded with pamidronate: fabrication and characterization, International Journal of Polymeric Materials and Polymeric Biomaterials, 32, 1089–1102 (2023). (I.F. =3.221) https://doi.org/10.1080/00914037.2022.2124252
  • Athira Murali, Vakkattil, M.A. & P. Ramesh, ‘Investigating the Effect of Processing Parameters on Mechanical Behavior of 3D Fused Deposition Modeling Printed Polylactic Acid’. J. of Materi Eng and Perform (2022). (IF=2.036) https://doi.org/10.1007/s11665-022-07188-3
  • Medha Surendranath, M R Rekha and P Ramesh, ‘Recent advances in developing functionally modified polymers for mucoadhesive drug delivery’, Journal of Materials Chemistry B DOI: 10.1039/d2tb00856d, Journal of Materials Chemistry B, 2022, 10, 5913 – 5924 (IF=7.571). https://doi.org/10.1039/D2TB00856D
  • Jasmin Joseph, P. Ramesh, G. Unnikrishnan, ‘Recent Advancements in Blended and Reinforced Polymeric Systems as Bioscaffolds’ International Journal of Polymeric Materials and Polymeric Biomaterials, 2022, https://doi.org/10.1080/00914037.2022.2066666 (I.F. =3.221)
  • Medha Surendranath, Resmi Rajalekshmi, Rekha M.R., Prakash Nair and P. Ramesh, ‘UV Crosslinked Electrospun Zein/PEO Fibroporous Membranes for Wound Dressing" ACS Applied Bio Materials 2022, 5, 4, 1538-1551 https://doi.org/10.1021/acsabm.1c01293.
  • P.V. Mayuri, Anugya Bhatt, A. Sabareeswaran and P. Ramesh, An explicit correlation between surface functionality, wettability, and leukocyte removal byelectrospun filter media, Materials Today Communications, 2021. 26, 102075. (I.F.=3.662) http://dx.doi.org/10.1016/j.mtcomm.2021.102075
  • P.V. Mayuri, Anugya Bhatt, A. Sabareeswaran, and P. Ramesh, Effect of membrane parameters and filter structure on the efficiency of leukocyte removal by electrospun poly(ethylene-co-vinyl alcohol) membranes, Journal of Biomaterials Science: Polymer Edition. 2021. 32: 595–612. (I.F.= 3.682) https://doi.org/10.1080/09205063.2020.1851559
  • S. Sreeja, P. Ramesh, P. R. Harikrishna Varma, G.S. Sailaja, Hierarchically Porous Osteoinductive Poly (Hydroxyethyl methacrylate-co-Methyl methacrylate) Scaffold for Consolidated Osteosarcoma treatment with Sustained Doxorubicin Delivery and Bone Defect Repair, ACS Biomaterials Science and Engineering. 2021. 7: 701–717 (I.F.= 5.395) https://doi.org/10.1021/acsbiomaterials.0c01628

Publications

Article

  1. Sunny, MC; Vincy, PV; Anil Kumar, PR; Ramesh, P., Porous composites of hydroxyapatite-filled poly [ethylene-co-(vinyl acetate)] for tissue engineering, Polymer International, 2011, 60; 51-58, http://onlinelibrary.wiley.com/doi/10.1002/pi.2973/full
  2. Velayudhan, S.; Ramesh, P.; Varma, HK, Mechanical properties of hydroxyapatite-filled ethylene vinyl acetate copolymer composites: Effect of particle size and morphology, Journal of Applied Polymer Science, 2011, 119, http://onlinelibrary.wiley.com/doi/10.1002/app.32812/abstract
  3. Velayudhan, S.; Ramesh, P.; Varma, HK, Hydroxyapatite Filled Ethylene Vinyl Acetate Copolymer Composites for Bone Substitute Applications, Trends in Biomaterials and Artificial Organs, 2010, 14
  4. Sunny, MC; Ramesh, P.; Mohanan, PV; George, KE, Metallocene based polyolefin: a potential candidate for the replacement of flexible poly (vinyl chloride) in the medical field, Polymers for Advanced Technologies, 2010, 21; 621-631, http://onlinelibrary.wiley.com/doi/10.1002/pat.1475/full
  5. Sailaja, G S; Ramesh, P; Varma, H K, Ultrastructural evaluation of in vitro mineralized calcium phosphate phase on surface phosphorylated poly(hydroxy ethyl methacrylate-co-methyl methacrylate)., J Mater Sci Mater Med, 2010, 21; 1183-93, http://www.ncbi.nlm.nih.gov/pubmed/20099010
  6. Gopalakrishnanchettiyar, Sailaja S; Mohanty, Mira; Kumary, Thrikkovil V; Valappil, Mohanan P; Parameshwaran, Ramesh; Varma, Harikrishna K, Surface-phosphorylated copolymer promotes direct bone bonding., Tissue Eng Part A, 2009, 15; 3061-9, http://www.ncbi.nlm.nih.gov/pubmed/19338435
  7. Abraham, Elizabeth K; Ramesh, P; Joseph, R, Determination of zinc diethyldithiocarbamate released into artificial sweat from natural rubber latex vulcanizates by HPLC., J Chromatogr Sci, 2007, 45; 1-5, http://www.ncbi.nlm.nih.gov/pubmed/17254376
  8. Sailaja, GS; Ramesh, P.; Varma, HK, Hydroxyapatite moldable formulation using natural rubber latex as binder, Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2007, 82; 231---238, http://onlinelibrary.wiley.com/doi/10.1002/jbm.b.30725/full
  9. Velayudhan, S.; Ramesh, P.; Varma, HK; Schmitt, S.; Friedrich, K., Stamp forming of hydroxyapatite filled ethylene vinyl acetate co-polymers: Process optimization using a right angle V-mould, Composites Part A: Applied Science and Manufacturing, 2007, 38; 1621---1629, http://dx.doi.org/10.1016/j.compositesa.2006.03.013
  10. Abraham, E.K.; Ramesh, P.; Joseph, R., Release of dithiocarbamates into artificial sweat from latex vulcanizates: Effects of the accelerator type and storage time, Journal of Applied Polymer Science, 2006, 102; 2055-2061, http://onlinelibrary.wiley.com/doi/10.1002/app.23449/pdf
  11. Sunny, MC; Ramesh, P.; George, KE, Effect of partial replacement of di (2-ethyl hexyl) phthalate, by a polymeric plasticizer, on the permeability and leaching properties of poly (vinyl chloride), Journal of Applied Polymer Science, 2006, 102; 4720-4727, DOI: 10.1002/app.24821
  12. Sailaja, G S; Ramesh, P; Kumary, T V; Varma, H K, Human osteosarcoma cell adhesion behaviour on hydroxyapatite integrated chitosan-poly(acrylic acid) polyelectrolyte complex., Acta Biomater, 2006, 2; 651-7, http://www.ncbi.nlm.nih.gov/pubmed/16899418
  13. Sailaja, GS; Ramesh, P.; Varma, HK, Swelling behavior of hydroxyapatite-filled chitosan-poly (acrylic acid) polyelectrolyte complexes, Journal of Applied Polymer Science, 2006, 100; 4716---4722, http://onlinelibrary.wiley.com/doi/10.1002/app.23058/pdf
  14. Abraham, E.K.; Ramesh, P.; Joseph, R.; Mohanan, PV; Remakumari, VM, Release of dithiocarbamates into sweat from natural rubber latex surgical gloves, Rubber chemistry and technology, 2005, 78; 674-681, http://cat.inist.fr/?aModele=afficheN&cpsidt=17278229
  15. Pradeesh, TS; Sunny, MC; Varma, HK; Ramesh, P., Preparation of microstructured hydroxyapatite microspheres using oil in water emulsions, Bulletin of Materials Science, 2005, 28; 383-390, http://www.springerlink.com/content/0666941g327077k4/
  16. Abraham, E.K.; Ramesh, P.; Joseph, R.; Kumari, TV; Mohanan, PV; Remakumari, VM, Relationship between in vitro cell culture cytotoxicity and sweat-extractable dithiocarbamates in natural rubber latex gloves, JOURNAL OF RUBBER RESEARCH-KUALA LUMPUR-RUBBER RESEARCH INSTITUTE OF MALAYSIA-, 2005, 8; 103
  17. Velayudhan, Shiny; Anilkumar, T V; Kumary, T V; Mohanan, P V; Fernandez, A C; Varma, H K; Ramesh, P, Biological evaluation of pliable hydroxyapatite-ethylene vinyl acetate co-polymer composites intended for cranioplasty., Acta Biomater, 2005, 1; 201-9, http://www.ncbi.nlm.nih.gov/pubmed/16701797
  18. Velayudhan, S.; Ramesh, P.; Varma, HK; Friedrich, K., Dynamic mechanical properties of hydroxyapatite-ethylene vinyl acetate copolymer composites, Materials Chemistry and Physics, 2005, 89; 454---460, http://dx.doi.org/10.1016/j.matchemphys.2004.10.004
  19. Sunny, MC; Ramesh, P.; George, KE, Use of polymeric plasticizers in polyvinyl chloride to reduce conventional plasticizer migration for critical applications, Journal of Elastomers and Plastics, 2004, 36; 19, http://jep.sagepub.com/content/36/1/19.abstract
  20. Sailaja, GS; Velayudhan, S.; Sunny, MC; Sreenivasan, K.; Varma, HK; Ramesh, P., Hydroxyapatite filled chitosan-polyacrylic acid polyelectrolyte complexes, Journal of Materials Science, 2003, 38; 3653-3662, http://www.springerlink.com/content/x6216r7762w3644w/
  21. Velayudhan, Shiny; Ramesh, P; Varma, H K, Effect of vinyl acetate content on the sintering behavior of hydroxyapatite-ethylene vinyl acetate copolymer composites., J Mater Sci Mater Med, 2002, 13; 517-22, http://www.ncbi.nlm.nih.gov/pubmed/15348606
  22. Abraham, E.K.; Ramesh, P., Natural Rubber Latex Products: Concerns in Health Care, Polymer Reviews, 2002, 42; 185-234
  23. Sunny, M C; Ramesh, P; Varma, H K, Microstructured microspheres of hydroxyapatite bioceramic., J Mater Sci Mater Med, 2002, 13; 623-32, http://www.ncbi.nlm.nih.gov/pubmed/15348570
  24. Ramesh, P; Joseph, R; Sunny, M C, A comparative evaluation of coefficient of friction and mechanical properties of commercially available Foley catheters., J Biomater Appl, 2001, 15; 344-50, http://www.ncbi.nlm.nih.gov/pubmed/11336387
  25. Abraham, E.K.; Francis, A.; Ramesh, P.; Joseph, R., Synthesis of calcium-containing methacrylate resin, Journal of Applied Polymer Science, 2001, 82; 2342-2346, DOI: 10.1002/app.2082
  26. Mohanan, PV; Joseph, R.; Ramesh, P.; Rathinam, K., Assessment of in Vivo Chromosomal Aberrations-Potency of Zinc Mercapto Benzo Thiazole, Journal of biomaterials applications, 2000, 14; 224, doi: 10.1177/088532820001400302
  27. Velayudhan, S.; Ramesh, P.; Sunny, MC; Varma, HK, Extrusion of hydroxyapatite to clinically significant shapes, Materials Letters, 2000, 46; 142-146, http://dx.doi.org/10.1016/S0167-577X(00)00157-9
  28. Joseph, R; Ramesh, P; Sivakumar, R, Tensile set behavior of Foley catheter balloons., J Biomed Mater Res, 1999, 48; 27-31, http://www.ncbi.nlm.nih.gov/pubmed/10029146
  29. Mohanan, PV; Joseph, R.; Ramesh, P.; Rathinam, K.; Sivakumar, R., Comparative intracutaneous irritation potential of three rubber accelerators, Toxicology Letters, 1998, 95; 174, http://dx.doi.org/10.1016/S0378-4274(98)80695-4