Accessibility Tools

Dr. Syam K.

2036 SYAM K

Contact Information

Address:

Dr. Syam K.
Professor
Neurology Department

Phone number:

4268(O), 0471-2924796 (R)

People - Neurology Department

Dr. Syam K.

Academic Qualifications

  • MBBS, Government Medical College, Kottayam, Kerala (Mahatma Gandhi University), 1998
  • MD, Government Medical College, Thiruvananthapuram, Kerala (University of Kerala), Internal Medicine (General Medicine), 2002
  • DM, Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), Thiruvananthapuram, Kerala, Neurology, 2005

Professional Record

  • December 2018 - Continuing : Professor of Neurology
  • January 2015 - December 2018: Additional Professor of Neurology, SCTIMST
  • January 2012 - December 2014: Associate Professor of Neurology, SCTIMST
  • January 2009 - December 2011: Assistant Professor of Neurology, SCTIMST
  • August 2008- December 2008: Senior Lecturer in Neurology, Government Medical College, Kozhikode, Kerala, India
  • February 2008- July 2008: Adhoc Consultant, Department of Neurology, SCTIMST.
  • January 2006 - January 2008 : Consultant Neurologist, St. Mary's Super-specialty Hospital, Thodupuzha, Kerala

Honors

  • Honorary Dean of the Faculty of Modern Medicine, Kannur University (2020-2022)
  • Best outgoing student- for MD (General Medicine), Medical College, Thiruvananthapuram (2002)
  • Second Rank in Mahatma Gandhi University for MBBS Examination (1997)

Awards

  • Travel Grant Award to attend the International Congress of Parkinson's disease and Movement Disorders, Madrid, Spain (September 2022)
  • Travel Grant Award to attend the International Congress of Parkinson's disease and Movement Disorders, Nice, France (September 2019)
  • Neurology India Award for the best research paper of 2016

Area of Interest

  • Movement Disorders
  • Cognitive Neurology in the Context of Movement Disorders

Collaboration

  • Cochin University of Science and Technology (CUSAT)- for the ICMR funded project on Gut Microbiome in Parkinson's disease

Membership

  • Member - International Parkinson and Movement Disorder Society (MDS)
  • Life member of Movement Disorder Society of India (MDSI)
  • Life member - Neurological Society of India (NSI)
  • Life member - Indian Academy of Neurology (IAN)
  • Life Member - Kerala Association of Neurologists (KAN)
  • Life member- Indian Medical association

On-going Projects

  • Principal Investigator- "Spiral Dx- Tremor Diagnosis using Artificial Intelligence" - Multicenter collaborative research project funded by the Department of Biotechnology, Government of India
  • Principal Investigator- Clinical Registry of Movement Disorders - Funded by the Movement Disorders Society of India
  • Co-Principal Investigator - Isolation and culturing of peripheral blood mononuclear cells in the buffy coat for selective differentiation into dopaminergic cells for cell-based therapeutic applications in Parkinson's disease (Funded by CUSAT, Kochi)
  • Co-Principal Investigator of the ICMR funded Project "Identification and Characterization of Ubiquitin and Neuronal-derived circulating exosomal cargoes in Parkinson's disease patients"
  • Co-Principal Investigator- Genetic Architecture of Parkinson's Disease in India (Funded by Michael J Fox Foundation, USA)
  • Co-Principal Investigator - Dementia Science Program- Incidence, prevalence and risk analysis of dementia and basic research thereof (Funded by Department of Biotechnology, Govt. of India)
  • PI/ Co-PI for non-funded projects on: Evaluation of Pain as a non-motor symptom in Parkinson's disease using King's Parkinson Pain Scale; Impact of diabetes on the motor and non-motor manifestations of Parkinson's disease; Survival of Indian patients with Parkinson's disease who have undergone Deep Brain Stimulation surgery; Surgical Complications of Deep Brain Stimulation; Natural history of isolated focal dystonia etc.

Projects Completed

  • Principal Investigator of ICMR-funded collaborative (with CUSAT, Kochi) project - Exploring the human gut microbiome, metabolome and alpha synuclein in health and Parkinson's disease (PD) - a window to the gut microbiota-brain axis alterations in PD.
  • Principal Investigator of DBT-funded project - Quantitative estimation of regional brain iron deposition- a potential biomarker for Parkinson's disease and other neurodegenerative conditions causing atypical Parkinsonism
  • Principal Investigator of ICMR-funded project - Validation of the Malayalam version of Montreal Cognitive Assessment (MoCA) scale and a prospective evaluation of mild cognitive impairment in Parkinson's disease using the Malayalam version (MoCA-M)
  • Co-Principal Investigator of the DST (SATYAM Program) funded project - Effects of Yoga on motor cortex plasticity, motor learning and motor deficits of Parkinson's disease
  • Evaluation of non-motor symptoms in patients with Parkinson's disease from Kerala using Non-Motor Symptoms Scale (NMSS)
  • Long-term follow-up of bilateral subthalamic nucleus deep brain stimulation for advanced Parkinson's disease patients
  • Do baseline clinical and Neuropsychological factors predict the occurrence of dementia on follow-up in patients with Parkinson's disease undergoing Deep Brain Stimulation surgery.
  • Apraxia of eye lid opening after bilateral Subthalamic nucleus Deep Brain Stimulation in Parkinson's disease

Professional Experience

  • 18 years of professional experience as a Neurologist, 16 years of professional experience as a teaching faculty in Neurology and 15 years of experience in the Neurological sub-specialty of Movement Disorders, as on December 31, 2023. Fifteen years of experience in specialized procedures like Deep Brain Stimulation and Botulinum Toxin Therapy for Movement Disorders

Desertations Supervised

  • Deep Brain Stimulation in Parkinson's disease: challenges in developing countries, a retrospective analysis from tertiary care centre
  • Clinical profile and outcome of focal and segmental dystonia in adults treated with botulinum toxin injection-A Retrospective study from a tertiary care center in India
  • Sleep disturbances in Parkinson's disease
  • Validation of Malayalam version of Montreal Cognitive Assessment (MoCA) for use in patients with Parkinson's disease
  • Hearing impairment in Parkinson's disease
  • Effect of subthalamic nucleus Deep Brain Stimulation Surgery on impulsivity in Parkinson's disease patients
  • Non-motor fluctuations in patients with Parkinson's disease
  • Non-conventional stimulation paradigms for refractory symptoms in patients undergoing Deep Brain Stimulation for Parkinson's disease
  • Non-motor symptoms in patients with different sub-types of Parkinson's disease
  • Progressive Supranuclear Palsy (PSP) - Application of the new MDS diagnostic criteria and prognosis of PSP sub-types
  • Lipid profile in Parkinson's disease
  • Gender influence on selection for DBS and outcome of DBS in Parkinson's disease
  • Cognitive effects of Deep Brain Stimulation in Parkinson's disease

Organisational Activities

  • Associate Editor, Annals of Indian Academy of Neurology (The official journal of Indian Academy of Neurology)
  • Member, Continuing Medical Education Committee , International Parkinson and Movement Disorder Society (2023-2025)
  • Member, Institutional Ethics Committee, Sree Chitra Tirunal Institute for Medical Sciences and Technology
  • Organized (As Organizing Secretary) the 5th Annual Conference of the Movement Disorders Society of India (MDSICON 2020), January 31- February 2, 2020, Kovalam , Thiruvananthapuram. The three-day scientific event was attended by nine International Faculty, around 70 National Faculty and 550 Delegates from across India and near- by SAARC countries.

Team

  • Professor of Neurology in-Charge of the Comprehensive Care Center for Movement Disorders (CCCMD), from December 2020

Presentations

  • International Parkinson and Movement Disorders Congress , Madrid, Spain (September 2022) : "Quantitative susceptibility mapping of basal ganglia and related structures: correlation with disease severity in Progressive Supranuclear Palsy"
  • 8th Asian and Oceanian Parkinson's disease and Movement Disorders, Kolkata, India (March 2023): "Deep Brain Stimulation for Motor Complications of Parkinson’s disease- considerations in a resource-poor setting"
  • International Parkinson and Movement Disorders Congress , Nice, France (September 22-26, 2019) : "Mild Cognitive Impairment in Parkinson's disease in South Indian population - Development of a test battery and assessment of prevalence and characteristics"
  • The Fourth Asian and Oceanian Parkinson's disease and Movement Disorders Congress (AOPMC 2014), November 28-30, Pattaya, Thailand: "Cross Cultural adaptation of Montreal Cognitive Assessment Scale retains in validity for use in patients with Parkinson's disease"
  • The Third Asian and Oceanian Parkinson's disease and Movement Disorders Congress (AOPMC 2011) and the 8th International Symposium of Asian and Pacific Parkinson Association, March 25th-27th, 2011, Taipei, Taiwan: "Non-motor Symptoms are ubiquitous in Parkinson's disease and distinct from normal aging: a case-control study using Non-Motor Symptoms Scale"
  • 19th Annual Conference of the Indian Academy of Neurology (IANCON 2011), September 22 -25, 2011, Pune. Title of the paper presented: "Ten years follow up of Subthalamic nucleus DBS for advanced Parkinson's disease"
  • Annual Conference of the Indian Academy of Neurology, 24th-27th October, 2013, Indore (IANCON 2013). Title of the paper presented: "Bilateral Subthalamic Nucleus Stimulation improves Non-Motor Symptoms in advanced Parkinson's disease"
  • 24th Annual Conference of the Indian Academy of Neurology, 10th - 13th November 2016, Kolkata. (IANCON 2016). Presented a research paper on "Dementia-free survival after bilateral subthalamic stimulation for Parkinson's disease"
  • 2nd Annual Conference of the Movement Disorders Society of India, 6th - 8th January 2017, Bangalore (MDSICON 2017). Presented a research paper on "What predicts an early onset of dementia in non-demented patients undergoing subthalamic stimulation for Parkinson's disease"

Invited talks

  • Invited Faculty- National CME on "Physiology in Clinical Practice- Strategies, Scope and Challenges". August 1, 2023. Organized by the Department of Physiology, AIIMS, Patna, Bihar. Topic: "Deep Brain Stimulation for Movement Disorders- Neurophysiology, Targets and Intra-operative monitoring"
  • Invited Faculty- 7th Annual Conference of Movement Disorders Society of India (MDSICON 2023). Kolkata, March 2023. Topic : "Drug repurposing in Movement Disorders"
  • Invited Faculty- KAN Monsoon Summit - International Neurology Update 2023- July 14-16, 2023, Kochi, India
  • Invited Faculty - Workshop on Neurodegeneration and Neurogenetics - the Future of Indian Collaboration. May 6th - 7th, Bangalore, India
  • Faculty for the 9th Clinical Teaching Program, Organized by the Kerala Association of Neurologists (KAN) (Medical College, Thiruvananthapuram; 21-22 January, 2023)
  • Invited Faculty- 6th Annual Conference of Movement Disorders Society of India (MDSICON 2021-2022); 13th-15th May 2022, Mumbai. Topic: "Understanding tremor syndromes"
  • Invited Faculty for Clinical Neurology Online Course, organized by the Pediatric neurology subsection of Indian Academy of Neurology. 12th June 2022. Topic : "The child with movement disorder - clinical approach"
  • Dr Jacob Roy Memorial CME- Cognitive Assessment in Adults . Thiruvananthapuram, December 18, 2022. Topic: : "Assessment of Praxis and Gait"
  • Invited faculty for the National Training Program on Deep Brain Stimulation, organized by the ECMT (European Continuing Medical Training) , Kochi , India (23- 24 April, 2022)
  • Annual Conference of the Kerala Association of Neurologists - Poovar, Thiruvananthapuram, 4th and 5th June, 2022. Topic: “Complex Case Scenarios in Movement Disorders- How do I manage?”
  • Invited Faculty for the Annual Conference of Neurological Society of India- Kerala Chapter (Travancore Neurocon -2022) - Kovalam, 6th - 8th May 2022. Topic: "Deep Brain Stimulation in Non-Parkinson’s disease Movement Disorders"
  • Faculty for the 8th Clinical Teaching Program, Organized by the Kerala Association of Neurologists (KAN) (Medical College, Alapuzha; 15th - 16th January, 2022)
  • Invited Faculty for the National CME (Conducted in Virtual mode) on "Add on therapies in Parkinson's disease- Wings of Change" , by NIMHANS, Bangalore (January 24, 2021). Delivered a talk on "Lesioning Surgeries and DBS in PD"
  • Faculty for the 7th Clinical Teaching Program, Organized by the Kerala Association of Neurologists (KAN) (Online mode; February 27-28, 2021)
  • Invited Faculty for the Movement Disorders Session in the "Virtual Agrim Neurology Update (VANU)" (16th - 18th October 2020) organized in Virtual Mode by the Agrim Neurosciences Trust, Indian Academy of Neurology and Movement Disorders Society of India
  • Invited Faculty for the 5th Annual Conference of The Movement Disorders Society of India (January 31- February 2, 2020, Kovalam, Thiruvananthapuram). Delivered a talk on "Tic Disorders and Tourette Syndrome"
  • Invited Faculty for the 44th Annual Conference of the Association of Physicians of India, Kerala Chapter (18th - 19th January, 2020). Delivered a lecture on "Diagnosis and Management of Parkinson's disease- a Pragmatic approach"
  • Faculty for the 6th Clinical Teaching Program, Organized by the Kerala Association of Neurologists (KAN) (Medical College, Kottayam; 4th -5th January, 2020)
  • Invited Faculty for the Deep Brain Stimulation in Movement Disorders course organized by the International Parkinson and Movement Disorder Society Asian and Oceanian Section (MDS-AOS) (Hyderabad, November 8-10, 2019). Participated in DBS Programming workshop
  • Invited Faculty for International CME "The 3D Approach to Movement Disorders" organized in Chennai by the Madras Neuro Trust (29- 31 August 2019). Delivered a faculty lecture on "Differential Diagnosis of Tic Disorders"
  • Invited Faculty for the 4th Annual Conference of the Movement Disorders Society of India (New Delhi, 22nd - 24th February, 2019), for the Deep Brain Stimulation workshop
  • Faculty for the 5th Clinical Teaching Program, Organized by the Kerala Association of Neurologists (KAN) (Medical College, Thiruvananthapuram; January 12-13, 2019)
  • Faculty for the mid term state conference of Kairali Neuroscience Society (Alapuzha, October 28, 2018). Delivered a lecture on "Diagnosis and Management of Dystonia"
  • Invited faculty in the live workshop and symposium on "Deep Brain Stimulation for Parkinson's disease" conducted by the Department of Neurosciences, Sree Venkateshwara Institute of Medical Sciences (SVIMS), Tirupati (25th - 26th May 2018)
  • Invited faculty for the Continuing Medical Education Program on Movement Disorders, organized by the Department of Neurosciences, Kasturba Medical College, Manipal, on 24th March, 2018 at Manipal. Delivered a lecture on "Surgery for Movement Disorders- Indications and pre-operative evaluation"
  • Invited faculty for the 7th Annual Conference of the Neurological Surgeons Society of India, 23rd- 25th February 2018, Lucknow (NSSICON 2018). Delivered a lecture on "Evaluation of patients with Movement Disorders and selection criteria for surgery"
  • Invited faulty for the Annual Conference of the Kairali Neuroscience Society, 10th - 11th February 2018, Kottayam. Delivered a lecture on "Deep Brain Stimulation for Parkinson's disease- when and in whom"
  • Invited faculty for the 3rd Annual Conference of the Movement Disorders Society of India, 19th - 21st January 2018, Hyderabad (MDSICON 2018). Delivered a lecture on "Impulse control disorders in Parkinson's disease and impact of Deep Brain Stimulation"
  • Faculty for the 4th Clinical Teaching Program, Organized by the Kerala Association of Neurologists (KAN)(Medical College, Alapuzha, 9th - 10th December 2017)
  • Invited faculty in the Continuing Medical Education program on Functional Neurosurgery for Parkinson's disease and Psychiatric disorders, organized by the Amrita Institute of Medical Sciences, Kochi (January 22, 2017). Delivered a lecture on Intra-operative monitoring and programming of DBS for Parkinson's disease.
  • Invited faculty in the two-day symposium on "Neural functions of the Ageing Brain" held at the Rajiv Gandhi Centre for Biotechnology (RGCB), Thiruvananthapuram (27th - 28th September, 2016). Delivered a lecture on "Relationship between ageing and Parkinson's disease- where do we stand"
  • Invited faculty for the Mid-term Meeting of Kerala Association of Neurologists held at Thiruvananthapuram (25th October 2015). Delivered a lecture on Psychogenic Movement Disorders.

Select Publications

Publications

Article

  1. Krishnan S, George SS, Radhakrishnan V, Raghavan S, Thomas B, Thulaseedharan JV, Puthenveedu DK., Quantitative susceptibility mapping from basal ganglia and related structures: correlation with disease severity in progressive supranuclear palsy., Acta Neurol Belg., 2023, doi: 10.1007/s13760-023-02352-5. Online ahead of print. PMID: 37580639, https://pubmed.ncbi.nlm.nih.gov/37580639/
  2. Vijayaraghavan A, Urulangodi M, Ajit Valaparambil K, Sundaram S, Krishnan S, Movement Disorders in GRIA2-Related Disorder – Expanding the Genetic Spectrum of Developmental Dyskinetic Encephalopathy., Mov Disord Clin Pract, 2023, 10(8):1222-1224. doi: 10.1002/mdc3.13797. eCollection 2023 Aug, https://pubmed.ncbi.nlm.nih.gov/37635778/
  3. Radhakrishnan V, Gallea C, Valabregue R, Krishnan S, Kesavadas C, Thomas B, James P, Menon R, Kishore A., Cerebellar and basal ganglia structural connections in humans: Effect of aging and relation with memory and learning., Front Aging Neurosci, 2023, 15:1019239. doi: 10.3389/fnagi.2023.1019239. eCollection 2023.PMID: 36776439, https://pubmed.ncbi.nlm.nih.gov/36776439/
  4. Patel Khushboo Subhas, Vijayaraghavan Asish, Krishnan Syam, Puthenveedu Divya Kalikavil., Huffing and puffing sign in functional axial jerks with secondary gait impairment., Annals of Movement Disorders, 2023, 6(1):30-32, Jan-Apr 2023., https://journals.lww.com/aomd/fulltext/2023/06010/huffing_and_puffing_sign_in_functional_axial_jerks.6.aspx
  5. Cherian A, Vijayaraghavan A, K.P. Divya, Krishnan S., Botulinum neurotoxin for the treatment of movement disorders: Practical considerations., Annals of Movement Disorders., 2022, 5(1):38-48, Jan-Apr 2022., https://journals.lww.com/aomd/fulltext/2022/05010/botulinum_neurotoxin_for_the_treatment_of_movement.4.aspx
  6. Patel K, Vijayaraghavan A, Krishnan S, Puthenveedu DK, Cherian A, Hemifacial spasm resulting from vertebrobasilar dolichoectasia in three siblings: A case report., Annals of Movement Disorders, 2022, 5(3):202-204, Sep-Dec 2022., https://journals.lww.com/aomd/fulltext/2022/05030/hemifacial_spasm_resulting_from_vertebrobasilar.10.aspx
  7. Cherian A, Divya KP, Vijayaraghavan A, Krishnan S., Pearls & Oy-sters: SCA21 Due to TMEM240 Variation Presenting as Myoclonus Dystonia Syndrome, Neurology, 2022, 99(12):531-534. doi: 10.1212/WNL.0000000000201015, https://pubmed.ncbi.nlm.nih.gov/36123134/
  8. Kishore A, James P, Rajeswari P, Sarma G, Krishnan S, Meunier S, Popa T., Depotentiation of associative plasticity is intact in Parkinson's disease with mild dyskinesia., Parkinsonism Relat Disord., 2022, May 1;99:16-22. doi: 10.1016/j.parkreldis.2022.04.019., https://pubmed.ncbi.nlm.nih.gov/35569298/
  9. Jain K, Ramesh R, Krishnan S (Corresponding author), Kesavapisharady K, Divya KP, Sarma SP, Kishore A., Cognitive outcome following bilateral subthalamic nucleus deep brain stimulation for Parkinson's disease-a comparative observational study in Indian patients., Acta Neurol Belg., 2022, 122(2):447-456. doi: 10.1007/s13760-021-01778-z. PMID: 34448152, https://pubmed.ncbi.nlm.nih.gov/34448152/
  10. Saraf U, Chandarana M, Divya KP, Krishnan S (Corresponding author)., Oromandibular dystonia -a systematic review., Ann Indian Acad Neurol., 2022, 25(1):26-34. doi: 10.4103/aian.aian_242_21. PMID: 35342238, https://pubmed.ncbi.nlm.nih.gov/35342238/
  11. Raina A, Rajan R, Sarma G, Krishnan S, Kesavapisharady K, Kishore A., Learning from negative consequences is impaired by STN-DBS and levodopa in Parkinson���s disease., Ann Mov Disord, 2021, 4:66-72., DOI: 10.4103/AOMD.AOMD_54_20
  12. Vijayaraghavan A, Cherian A, Kalikavil Puthenveedu D, Krishnan S, Pavuluri H., Anti Zic4 Paraneoplastic Neurological Syndrome Presenting as Oscillopsia., Mov Disord Clin Pract., 2021, 8(7):1134-1136. doi: 10.1002/mdc3.13331., https://pubmed.ncbi.nlm.nih.gov/34631952/
  13. Saraf UU, Jose J, Krishnan S, Sreedharan SE., Mucopolysacharidosis Type I Presenting as Bipolar Affective Disorder: A Case Report., Neurol India, 2021, 69:1753-5, https://pubmed.ncbi.nlm.nih.gov/34979681/
  14. Kishore A, James P, Popa T, Thejaus A, Rajeswari P, Sarma G, Krishnan S, Meunier S., Plastic responsiveness of motor cortex to paired associative stimulation depends on cerebellar input, Clin Neurophysiol., 2021, 132(10):2493-2502. doi: 10.1016/j.clinph.2021.06.029. PMID: 34454278., https://pubmed.ncbi.nlm.nih.gov/34454278/
  15. Chandarana MV, Cherian A, K P D, Krishnan S, Glenda M, Saraf U, Writer's cramp presentation of Woodhouse-Sakati Syndrome- "out of the woods", Can J Neurol Sci., 2021, Aug 24:1-9. doi: 10.1017/cjn.2021.201. PMID: 34425922., https://pubmed.ncbi.nlm.nih.gov/34425922/
  16. Chandarana M, Saraf U, Divya KP, Krishnan S (Corresponding author)., Huntington's disease presenting as adult-onset Tourettism: a case report., Ann Mov Disord, 2021, 4:153-6, https://www.aomd.in/text.asp?2021/4/3/153/333359
  17. Cherian A, Chandarana M, Susvirkar AA, Divya KP, Saraf UU, Krishnan S, Abnormal Saccades Differentiate Adolescent Onset Variant Ataxia Telangiectasia from Other Myoclonus Dystonia, Ann Indian Acad Neurol., 2021, Jul- Aug;24(4):630-632, https://pubmed.ncbi.nlm.nih.gov/34728979/
  18. Saraf U, Chandarana M,Divya KP, Krishnan S., ADCY5-related dyskinesia with myoclonus-dystonia syndrome: Clues to diagnosis., Ann Mov Disord 2021, 2021, 4:86-8, https://www.aomd.in/preprintarticle.asp?id=318092
  19. Cherian A, Paramasivan NK, Puthanveedu DK, Krishnan S, Nair AR., Generalized Chorea Due to Secondary Polycythemia Responding to Phlebotomy, J Mov Disord, 2021, Jan;14(1):89-91, https://pubmed.ncbi.nlm.nih.gov/33121224
  20. Mahale RR, Krishnan S, Divya KP, Jisha VT, Kishore A., Gender differences in progressive supranuclear palsy., Acta Neurol Belg., 2021, Feb 17., https://pubmed.ncbi.nlm.nih.gov/33595832/
  21. Cherian A, K P D, Paramasivan NK, Krishnan S., Pearls & Oy-sters: Levodopa-Responsive Adult NCL (Type B Kufs Disease) Due to CLN6 Mutation., Neurology., 2021, May 25;96(21):e2662-e2665., https://pubmed.ncbi.nlm.nih.gov/33875558
  22. Zafar SM, Rajan R, Krishnan S, Kesavapisharady K, Kishore A., Interleaved Stimulation for Freezing of Gait in Advanced Parkinson's Disease., Neurol India., 2021, Mar-Apr;69(2):457-460., https://pubmed.ncbi.nlm.nih.gov/33904475
  23. Mahale RR, Krishnan S, Divya KP, Jisha VT, Kishore A., Subtypes of PSP and Prognosis: A Retrospective Analysis., Ann Indian Acad Neurol., 2021, Jan-Feb;24(1):56-62., https://pubmed.ncbi.nlm.nih.gov/33911380
  24. Krishnan S (Corresponding author), Shetty K, Puthanveedu DK, Kesavapisharady K, Thulaseedharan JV, Sarma G, Kishore A., Apraxia of Lid Opening in Subthalamic Nucleus Deep Brain Stimulation for Parkinson's Disease-Frequency, Risk Factors and Response to Treatment., Mov Disord Clin Pract., 2021, Apr 12;8(4):587-593., https://pubmed.ncbi.nlm.nih.gov/33981792
  25. Saraf U, Chandarana M, Puthenveedu DK, Kesavapisharady K, Krishnan S(Corresponding author), Kishore A., Childhood-Onset Dystonia Attributed to Aicardi-Goutieres Syndrome and Responsive to Deep Brain Stimulation., Mov Disord Clin Pract., 2021, Apr 19;8(4):613-615., https://pubmed.ncbi.nlm.nih.gov/33981798
  26. Mitesh Chandarana, Udit Saraf, Divya K.P., Syam Krishnan, Asha Kishore., Myoclonus - a review., Ann Indian Acad Neurol., 2021, 2021 Epub ahead of print., https://dx.doi.org/10.4103/aian.AIAN_1180_20
  27. Krishnan S, Pisharady KK, Rajan R, Sarma SG, Sarma PS, Kishore A., Predictors of dementia-free survival after bilateral subthalamic deep brain stimulation for Parkinson's disease., Neurol India., 2019, Mar-Apr;67(2):459-466., https://www.ncbi.nlm.nih.gov/pubmed/31085861
  28. Shetty K, Krishnan S (Corresponding Author), Thulaseedharan JV, Mohan M, Kishore A., Asymptomatic Hearing Impairment Frequently Occurs in Early-Onset Parkinson's Disease., J Mov Disord., 2019, May;12(2):84-90., https://www.ncbi.nlm.nih.gov/pubmed/30944288
  29. Kishore A, Ashok Kumar Sreelatha A, Sturm M, von-Zweydorf F, Pihlstrom L, Raimondi F, Russell R, Lichtner P, Banerjee M, Krishnan S, Rajan R, Puthenveedu DK, Chung SJ., Understanding the role of genetic variability in LRRK2 in Indian population., Mov Disord., 2019, Apr;34(4):496-505., https://www.ncbi.nlm.nih.gov/pubmed/30485545
  30. Rajan R, Krishnan S, Sarma G, Sarma SP, Kishore A., Dopamine Receptor D3 rs6280 is Associated with Aberrant Decision-Making in Parkinson's Disease., Mov Disord Clin Pract., 2018, Jul 19;5(4):413-416., https://www.ncbi.nlm.nih.gov/pubmed/30363458
  31. Krishnan S, Pisharady KK, Divya KP, Shetty K, Kishore A., Deep Brain Stimulation for Movement disorders., Neurol India., 2018, Mar-Apr;66(Supplement):S90-S101., https://www.ncbi.nlm.nih.gov/pubmed/29503331
  32. Kishore A, Popa T, James P, Krishnan S, Robert S, Meunier S., Severity of Writer's Cramp is Related to Faulty Motor Preparation., Cereb Cortex, 2018, Oct 1;28(10):3564-3577., https://www.ncbi.nlm.nih.gov/pubmed/28968878
  33. Popa T, Hubsch C, James P, Richard A, Russo M, Pradeep S, Krishan S, Roze E, Meunier S, Kishore A, Abnormal cerebellar processing of the neck proprioceptive information drives dysfunctions in cervical dystonia., Sci Rep. (Scientific Reports, Nature Publishing Group), 2018, 8(1):2263, https://www.ncbi.nlm.nih.gov/pubmed/29396401
  34. Joseph PS, Syam Krishnan, Narayanappa G, Nair M., Young onset Parkinsonism in a patient with familial central core disease., Neurol India., 2017, 65:386-388, https://www.ncbi.nlm.nih.gov/pubmed/28290406
  35. Krishnan S, Pisharady KK, Surgical treatment of levodopa-induced dyskinesia in parkinson's disease, Ann Indian Acad Neurol., 2017, 20:199-206, http://www.annalsofian.org/article.asp?issn=0972-2327;year=2017;volume=20;issue=3;spage=199;epage=206;aulast=Krishnan
  36. Kishore A, James P, Krishnan S, Yahia-Cherif L, Meunier S, Popa T., Motor cortex plasticity can indicate vulnerability to motor fluctuation and high L-DOPA need in drug-naive Parkinson's disease., Parkinsonism Relat Disord., 2017, 35:55-62, https://www.ncbi.nlm.nih.gov/pubmed/28003105
  37. Rajan, R., Krishnan, S., Kesavapisharady, K. K. and Kishore, A., Malignant Subthalamic Nucleus-Deep Brain Stimulation Withdrawal Syndrome in Parkinson's Disease., Mov Disord Clin Pract,, 2016, 3: 288?291., http://onlinelibrary.wiley.com/doi/10.1002/mdc3.12271/full
  38. Krishnamoorthy S, Rajan R, Banerjee M, Kumar H, Sarma G, Krishnan S, Sarma S, Kishore A., Dopamine D3 receptor Ser9Gly variant is associated with impulse control disorders in Parkinson's disease patients., Parkinsonism Relat Disord., 2016, 30:13-7., https://www.ncbi.nlm.nih.gov/pubmed/27325396
  39. Krishnan S, Prasad S, Pisharady KK, Sarma G, Sarma SP, Kishore A, The decade after subthalamic stimulation in advanced Parkinson's disease: A balancing act., Neurol India., 2016, 64(1):81-9, http://www.ncbi.nlm.nih.gov/pubmed/26754997
  40. Krishnan S, Justus S, Meluveettil R, Menon RN, Sarma SP, Kishore A., Validity of Montreal Cognitive Assessment in Non-English speaking patients with Parkinson's disease., Neurol India., 2015, 63(1):63-7., http://www.ncbi.nlm.nih.gov/pubmed/25751471
  41. Syambabu Chandran, Syam Krishnan, Gangadhara Sarma S, Sankara sarma P, Asha Kishore., Gender influence on selection and outcome of deep brain stimulation for Parkinson's disease., Ann Indian Acad Neurol, 2014, 17:66-70., http://www.ncbi.nlm.nih.gov/pubmed/24753663
  42. Kishore A, Popa T, Balachandran A, Chandran S, Pradeep S, Backer F, Krishnan S, Meunier S, Cerebellar sensory processing alterations impact motor cortical plasticity in Parkinson's disease: clues from dyskinetic patients., Cereb Cortex., 2014, 24(8):2055-67, http://www.ncbi.nlm.nih.gov/pubmed/23535177
  43. Sarathchandran S, Soman S, Sarma SG, Krishnan S, Kishore A., Impulse control disorders in Indian patients with Parkinson's disease., Mov Disord, 2013, 28: 1901-1902., http://www.ncbi.nlm.nih.gov/pubmed/23801595
  44. Binitha Rajeswari, Syam Krishnan, Sarada C, Kusumakumary Parukuttyamma, Guillain Barre Syndrome with acute lymphoblastic leukemia., Indian Pediatrics, 2013, 50: 791-792., http://www.ncbi.nlm.nih.gov/pubmed/24036643
  45. Krishnan S, Sarma G, Sarma S, Kishore A., Do nonmotor symptoms in Parkinson's disease differ from normal aging?, Mov Disord., 2011, 26(11):2110-3., http://www.ncbi.nlm.nih.gov/pubmed/21661056
  46. Behari M, Bhattacharyya KB, Borgohain R, Das SK, Ghosh B, Kishore A, Krishnan S, Mridula KR, Muthane U, Pal PK, Sankhla C, Shukla G., Parkinson's disease, Ann Indian Acad Neurol, 2011, 14(Suppl 1):S2-6., http://www.ncbi.nlm.nih.gov/pubmed/21847323
  47. Lekha Pandit, Maria Ban, Stephen Sawcer, Bhim Singhal, Syam Nair, Kurupath Radhakrishnan, Rajesh Shetty, Z Misri, Suresh Hegde, Irruvathur Gopalakrishna Bhat., Evaluation of the established non-MHC Multiple Sclerosis loci in an Indian population., Mult Scler., 2011, 17(2):139-43., http://www.ncbi.nlm.nih.gov/pubmed/20952449
  48. Mahesh Pundlik Kate, Chandrasekharan Kesavadas, Muralidharan Nair, Syam Krishnan, Manoj Soman, Atampreet Singh., Late-onset Boucher-Neuhauser Syndrome (late BNS) associated with white-matter changes: a report of two cases and review of literature., J Neurol Neurosurg Psychiatry, 2011, 82(8):888-91., http://www.ncbi.nlm.nih.gov/pubmed/20587490
  49. Kishore A, Rao R, Krishnan S et al., Long term stability of effects of subthalamic stimulation in Parkinson?s disease: Indian experience., Mov Disord., 2010, 25:2438-44., http://www.ncbi.nlm.nih.gov/pubmed/20976738
  50. Neeraj N. Baheti, Syam Krishnan, Bejoy Thomas, Chandrasekharan Kesavadas, Ashalatha Radhakrishnan., Stroke like episodes in Sturge-Weber syndrome., Neurol India, 2010, 58(5):797-9, http://www.ncbi.nlm.nih.gov/pubmed/21045522
  51. Baheti NN, Hassan H, Rathore C, Krishnan S, Kesavadas C., Acquired hepatolenticular degeneration: is the T1 hyperintensity due to manganese deposition?, Neurol India., 2009, 57(6):812-3, http://www.ncbi.nlm.nih.gov/pubmed/20139522
  52. Baheti NN, Cherian A, Kate M, Krishnan S, Thomas B., Intracerebral hemorrhages in Vogt-Koyanagi-Harada disease., Neurol India., 2009, 57(6):815-7., http://www.ncbi.nlm.nih.gov/pubmed/20139524
  53. Syam Krishnan, PS Mathuranath, Sankara Sarma, Asha Kishore., Neuropsychological functions in progressive supranuclear palsy, multiple system atrophy and Parkinson?s disease., Neurol India., 2006, 54(3):268-72., http://www.ncbi.nlm.nih.gov/pubmed/16936386
  54. Khan SF, Ashalatha R, Syam K., Periodic EEG pattern in neuro-dengue -- a novel observation, Eur J Neurol., 2005, 12(12):1009.

Book Chapter

  1. Krishnan S, Autoimmune Movement Disorders., Ranganathan L N, Krishnan M, Iyer RS (Editors). Monograph Immune Mediated Neurological Disorders, 1st Edition,, 2022, Page 67-75. ISBN: 9789352704514., Jaypee Brothers Publishers, New Delhi
  2. Kesavapisharady K, Krishnan S, Role of lesioning procedures in the Deep Brain Stimulation era., In: Paniker D et al. (Editors). Progress in Clinical Neurosciences Volume, First Edition., 2022, Page 135-138. ISBN 978-93-90553-94-5., Thieme Medical and Scientific Publishers, Mumbai
  3. Asish Vijayaraghavan, Patel Khushboo Subhash, Divya KP, Syam Krishnan., Tremor disorders, In: Ranganathan L N (Editor). Reviews in Neurology 2020. Movement Disorders: Indian Perspective, 2021, Page 94-105. ISBN: 978-93- 90612-88-8. ISSN: 0971-5924, Wolters Kluwer (India) Pvt. Ltd., New Delhi
  4. Krishnan S, Kishore A., Parkinson's disease., In: Shirly G, S K Kunnath, Anne Varghese, Vinitha Mary George (Editors) Disability: An Overview, In the Context of the Rights of Persons with Disabilities (RPwD) Act, 2016., 2019, Page 241-260. ISBN: 9788193985007, NISH (National Institute of Speech and Hearing)
  5. Krishnan S, Rajan R, Kishore A., Deep brain stimulation for movement disorders., In: Mukherjee A (Editor-in-Chief). IAN Textbook of Neurology. 1st Edn. New Delhi., 2018, Page 415-421. ISBN 978-93-5270-179-7, Jaypee Brothers Medical publishers