Dr. Jyothi E. K.

Academic Qualifications

• PhD in Neuromicrobiology, National Institute of Mental Health and Neuro Sciences (NIMHANS), Bangalore . 2015
• MSc Medical Microbiology, Faculty of Medicine, University of Calicut, 2008
• BSc Medical Microbiology, Faculty of Medicine, University of Calicut, 2006

Professional Record

• Scientist C, Dept of Microbiology, SCTIMST, Trivandrum. August 2018
• Program Manager, The Accelerator program for Discovery in Brain disorders using Stem cells (ADBS), NIMHANS, Bangalore. 2018
• Consultant/ Technical Coordinator, Paediatric CBNAAT project with RNTCP (Bangalore, Guwahati, Indore, Nagpur, Surat, and Vizag): Accelerating access to quality TB diagnosis for paediatric cases, Foundation for Innovative New Diagnostics (FIND India). 2017
• Product Specialist, Tuberculosis Franchise and Women's Health (South India), QIAGEN India. 2015

Honors

• First Rank, MSc Medical Microbiology (Faculty of Medicine), University of Calicut 2008
• Post Graduate Indira Gandhi Scholarship, UGC 2006
• First Rank, BSc Medical Microbiology (Faculty of Medicine), University of Calicut 2006

Awards

• Best Paper Award for "Evaluation of the Genotype MTBDRplus assay for Rifampicin and Isoniazid susceptibility testing using direct cerebrospinal fluid samples" at Annual Conference and CME, Indian Association of Medical Microbiologists (KC), Mangalore. 23-24th February, 2013.
• Best Poster Award for "Multifaceted Study of Cryptococcus neoformans to Annotate its Genome, host-pathogen relation and Signalling" at the International symposium on "Proteomics beyond IDs" and 4th annual meeting of Proteomics Society of India, 22-24th November, 2012 (as Co-author).

Area of Interest

• Neuroinfections, Clinical microbiology, Clinical proteomics, Molecular diagnosis, Rapid diagnostic devices

Current Activities

• Research and in vitro Diagnosis

Patents

• Test kit for detecting Chlamydia trachomatis - 202041053682 (applied)
• Test kit for determination of procalcitonin - 202041043487 (applied)
• Development of Antibody detection for SARS CoV 2- 202041015212 (applied)

Fellowships

• Senior Research Fellowship, ICMR. 2011
• Junior Research Fellowship, ICMR. 2009

Membership

• Indian Association of Medical Microbiologists (IAMM)

On-going Projects

• Whole Genome Sequencing to understand the evolution of COVID 19 clusters in healthcare workers and inpatients in a non-COVID tertiary care hospital and the impact of vaccination and selection pressure on the genome of SARS CoV2. 2021- 2022.
• Development and Evaluation of Air borne infection control systems for healthcare facilities. 2020-2023 (Co-investigator)
• Development of rapid diagnostic kits for sepsis and Chlamydia trachomatis. 2020-2022
• Point care of detection of Human Papilloma virus using loop mediated amplification of DNA. 2019-2021 (Co-investigator)

Projects Completed

• Development of real time RT-PCR assay for detection of SARS-CoV-2. 2020-2021
• Rapid Diagnostic Kits for SARS-CoV-2 Detection. (Co-investigator) 2020
• Development of a rapid technique for identification and characterization of clinical Acinetobacter baumannii isolates using Raman spectroscopy 2019-2020

Select Publications

Reviewer

• Indian Journal of Tuberculosis

Publications

Article

1. Gopika Ramesh, Willi Paul,Vishal Valparambil Puthanveetil, Kavita Raja, Jyothi Embekkat Kaviyil, Raman spectroscopy as a novel technique for the identification of pathogens in a clinical microbiology laboratory, Spectroscopy Letters, 2022,
2. Gopika R, Jyothi EK, Willi P, Renjith S, Roy J, Gallium-Curcumin Nanoparticle Conjugates as an Antibacterial Agent against Pseudomonas aeruginosa: Synthesis and Characterization., ACS Omega, 2022,
3. R Sasi, SL Sreejith, G Ramesh, DR Sherin, JE Kaviyil, W Paul, R Joseph, Ionic liquid based antimicrobial coating on polymeric surface: A green chemistry approach., Results in Surfaces and Interfaces, 2021,
4. Ponnambath DK, Gopalakrishnan A, Pillai VV, Kaviyil JE, Raja K., Clinical profile of prosthetic valve endocarditis (PVE) due to Candida parapsilosis: A 11-year retrospective observational study from a quaternary cardiac referral Institute in India, IJCCM, 2021,
5. M Vani, EK Jyothi, KP Dinoop, PN Renjith, B Anugya, P Rajendra, V Lathika, D Ranjeet, AV Ramdas, and G Manoj, Evaluation of diagnostic accuracy of developed rapid SARS-COV-2 IgG antibody test kit using novel diluent system, VirusDisease, 2021,
6. Gurpreet Singh, G Srinivas, EK Jyothi, LK Gayatri, Rakhal Gaitonde, Biju Soman, Containing the first outbreak of COVID-19 in a healthcare setting in India: The Sree Chitra experience, Ind J Public Healh, 2020,
7. Kaviyil JE, Ravikumar R., Diagnosis of Tuberculous Meningitis: Current Scenario from a Tertiary Neurocare Centre in India., Ind J Tubercuosis, 2017, 64(3):183-188, https://www.ncbi.nlm.nih.gov/pubmed/?term=indian+journal+of+tuberculosis%C2%A02017+Jul%3B+64(3)%3A183-188.
8. Datta KK, Patil A H, Patel K, Dey G, Madugundu AK, Renuse S, Kaviyil JE, Nirujogi RS, Arunima A, Daswani B, Kaur I, Mohanty J, Sinha R, Jaiswal S, Sivapriya S, Sonnathi Y, Chattoo BB, Gowda H, Ravikum, Proteogenomics of Candida tropicalis - an opportunistic pathogen with importance for global health., OMICS: A Journal of Integrative Biology, 2016, 20(4): 239-47, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840825/
9. Uppu DSSM, Manjunath GB, Yarlagadda V, Kaviyil JE, Ravikumar R, Paramanandham K, Shome BR, Haldar J, Membrane-Active Macromolecules Resensitize NDM-1 Gram-Negative Clinical Isolates to Tetracycline Antibiotics., PLoS ONE, 2015, 10(3):e0119422, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366164/
10. Shenoy AK, Jyothi EK, Ravikumar R., Phenotypic identification and molecular detection of blaNDM-1 gene in multidrug resistant Gram negative bacilli in a tertiary care centre, Ind J Med Res, 2014, 139:625-31, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078503/
11. Selvan LDN, Renuse S, Jyothi EK, Sharma J, Pinto SM, Yelamanchi SD, Puttamallesh VN, Ravikumar R, Pandey A, Prasad TSK, Harsha HC, Phosphoproteome of Cryptococcus neoformans, J Proteomics, 2014, .97: 28795, https://www.ncbi.nlm.nih.gov/pubmed/23851311
12. Selvan LDN, Kaviyil JE, Nirujogi RS, Muthusamy B, Puttamallesh VN, Subbannayya T, Syed N, Radhakrishnan A, Kelkar DS, Ahmad S, Pinto SM, Kumar P, Madugundu AK, Nair B, Chatterjee A, Pandey A, Ravikuma, Proteogenomic analysis of pathogenic yeast Cryptococcus neoformans using high resolution mass spectrometry, Clin Proteomics, 2014, 11(1):5, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915034/
13. Ravikumar R, Jyothi EK, Nanda Kumar BS, Murthy MMR, Efficacy of air disinfection devices in controlling atmospheric microflora in enclosed health care settings, J Evol Med Dent Sc., 2012, 1(5):715-22, https://jemds.com/latest-articles.php?at_id=241
14. Ravikumar R, Jyothi EK, Dutta BS, Vidyasagar K, Nandan TM, Ashalatha G, Infections by multidrug resistant organisms in a Neurosurgical and Neuropsychiatric care centre and the changing antimicrobial susceptibility patterns, J Evol Med Dent Sc., 2012, 1(4):445-52, https://jemds.com/latest-articles.php?at_id=180

Case Report

1. Jyothi Embekkat Kaviyil, Dinoop Korol Ponnambath, Bijulal Sasidharan, Pravi Vidyadharan, Kavita Raja, Aggregatibacter aphrophilus, a HACEK group pathogen as a cause of prosthetic valve endocarditis, J of Acad Clin microbiol., 2022,
2. 3. Dinoop Korol Ponnambath, Jyothi Embekkat Kaviyil Kavita Raja, Krishnakumar Kesavapisharady, Bejoy Thomas, Deepti Narasimhaiah, Rakesh Sehgal, Upninder Kaur, An unusual guest in an unusual location of the brain of a rural tribal man, J of Acad Clin microbiol., 2022,
3. Ponnambath DK, Kaviyil JE, Raja K, Abraham M, Thomas B., A rare case of cellular abscess due to Listeria monocytogenes in an elderly patient with ulcerative colitis, Neurology India, 2019,
4. Kaviyil JE, Pitchai S, Ponnambath DK, Raja K, Mycotic aneurysm by non- typhoidal Salmonella, J of Acad Clin microbiol., 2019,
5. Ponnambath DK, Kimji PB, Kaviyil JE, Raja K, Vilanilam GC, Thomas B., First report of intracranial epidermoid cyst infection and brain abscess caused by Salmonella Paratyphi A., J of Acad Clin microbial., 2019,