Dr. TV Anilkumar

Academic Qualifications

• Cert LAM (2012, University of Guelph, Canada): Post-doctoral Certificate in Laboratory Animal Medicine
• PhD, Faculty of Medicine (1996, University of London): Imperial College School of Medicine at Hammersmith (Royal Postgraduate Medical School
• MSc Experimental Pathology and Toxicology (1991, University of London), Royal Postgraduate Medical School
• MVSc, Veterinary Pathology (1986, Kerala Agricultural University), Centre of Excellence in Pathology, College of Veterinary &Animal Sciences, Mannuthy
• BVSc&AH, Veterinary Science and Animal Husbandry) (1983, Kerala Agricultural University), Thrissur, India.

Professional Record

• Scientist-G (Veterinary Pathology), Since January 2016
• Scientist-F (Veterinary Pathology), Sree Chitra Tirunal Institute for Medical Sciences and Technology, January 2012 to date
• Scientist-E (Veterinary Pathology), Sree Chitra Tirunal Institute for Medical Sciences and Technology, January 2008 to December 2011
• Scientist-E (Veterinary Pathology), Sree Chitra Tirunal Institute for Medical Sciences and Technology, January 2004 to December 2007
• Scientist-C (Veterinary Pathology), Sree Chitra Tirunal Institute for Medical Sciences and Technology, January 2000 to December 2003
• Assistant Professor (Veterinary Pathology), Kerala Agricultural University, November 1995 to January 2000
• Research Scientist (Veterinary Surgeon), Sree Chitra Tirunal Institute for Medical Sciences and Technology, November 1987- September 1990
• Junior Assistant Professor, Kerala Agricultural University, November 1985 to November 1987

Honors

• Since 2013: Adjunct professor, Kerala Veterinary and Animal Sciences University, Pookode, Wayanad
• Since October 2020: Visiting Professor, School of Biology, Indian Institute of Science Education and Research-Thiruvananthapuram, Vithura
• Cutting Edge Research Enhancement and Scientific Training (CREST-Award: Department of Biotechnology), Government of India for taking up Visiting Scientist position at the Department of Molecular Pathobiology, School of Medicine in Johns Hopkins University, Baltimore, USA for 12 months from February 2012 (7 months).-2011
• Dr. CM Singh Award: Indian Association of Veterinary Pathologists for the Best research article published in the Indian Journal of Veterinary Pathology-2007
• Dr PP Gupta Oration Award of the Indian Association of Veterinary Pathologists for outstanding contributions in Toxicologic Pathology. (Note: This award is given to a senior and reputed veterinary pathologist every year for their outstanding contribution)-2006
• ORS Award (Overseas Research Students Award) for studies at the Imperial College School of Medicine at Hammersmith) leading to PhD of the University of London. The award was administered by The Committee of The Principals and Vice Chancellors in the UK and selection was based on international merit. 1991-95
• ODASSS Award (Overseas Development Agency Shared Scholarship Scheme) for studies at the Royal Postgraduate Medical School, Hammersmith Hospital (MSc: Toxicology and Experimental Pathology, University of London). It was a highly competitive international award administered by the Association of Commonwealth, London on an international platform., 1990

Area of Interest

• Experimental and Toxicological Pathology
• Use of animal-derived extracellular matrix for Tissue Engineering and Regenerative Medical applications
• Pathology of Laboratory Animals
• Laboratory Animal Medicine/Welfare

Current Activities

• Consultant Experimental and Toxicological Pathology

पेटेंट

• Pandit A and Anilkumar TV (US Patent 7550152, June, 2009; Application. No. 11226035 filed on 09/14/2005): Tissue graft scaffold made from cholecyst-derived extracellular matrix
• TV Anilkumar and A Pandit (Irish Patent 84394, 2006): Tissue graft scaffold
• Anilkumar TV (877/CHE/2012): A simplified procedure for isolating tissue-engineering-scaffolds from small intestinal submucosa of warm blooded animals
• Anilkumar TV (985/CHE/2012): A simplified procedure for isolation of tissue-engineering-scaffold from cholecyst
• Anilkumar TV (1176/CHE/2012): A simplified procedure involving pre-isolation in situ cross linking of biomolecules for isolating tissue-engineering-scaffolds from urinary bladder of warm blooded animals
• Revi D and Anilkumar TV (2338/CHE/2013): A procedure for fabricating xenograft using mammalian cholecyst-derived extracellular matrix for wound healing applications
• Anoop S, Anilkumar TV, Syam KV (5649/CHE/2013): A method for fabricating corneal-grafts using mammalian cholecyst-derived extracellular matrix.
• Dhanush Krishna, ND Nair, Syam KV and Anilkumar TV (6135/CHE/2013): A procedure for fabricating and using decellularized porcine cholecyst as muscle graft for repairing full or partial thickness abdominal defect/hernia.
• Revi D, Anoopkumar T and Anilkumar TV (6194/CHE/2013): A method for fabricating skin-graft by loading cells on cholecyst extracellular matrix for wound healing applications

Fellowships

• 2019: Fellow, Royal College of Pathologists
• Fellow, Royal Society of Biology (England)
• Visiting Faculty (01 March to 30 September 2012): Department of Molecular and Comparative Pathobiology, John Hopkins University, Baltimore, USA
• Post-Doctoral Fellowship in Tissue engineering (November, 2003 - September, 2004): National centre for Biomedical Engineering Sciences National, National University of Ireland, Republic of Ireland
• Visiting Scientist: 01 September to 31 October, 1996 (Royal Postgraduate Medical School, Hammersmith Hospital, London, UK

Membership

• FIATP, Fellow of the International Academy of Toxicologic Pathology, 2013
• DICVP, Diplomate of the Indian College of Veterinary Pathologists, 2008
• FIAVP, Fellow of the Indian Association of Veterinary Pathologists, 2008
• FRMS, Fellow, Royal Micrioscopical Society, Oxford, UK, 1994

Team

• Mrs. CS Geetha, Junior Scientific Officer

प्रकाशन

Article

1. Muhamed J, Revi d, Geetha S, Rajan A, Anilkumar T, Biocompatibility and immunophenotypic characterizationof a porcine cholecyst–derived scaffold implanted in rats, Toxicologic Pathology, 2015, 43(4):, http://www.ncbi.nlm.nih.gov/pubmed
2. Muhamed J, Revi D, Rajan A, Anilkumar T, Comparative local immunogenic potential of scaffolds prepared from porcine cholecyst, jejunum and urinary bladder in rat subcutaneous model, J Biomed Mater Res B Appl Biomater, 2015, 103(6);, http://onlinelibrary.wiley.com/doi/10.1002/jbm.b.33296/abstract
3. Revi D, Vineetha VP, Muhamed J, Surendran GC, Rajan A, Kumary T, Anilkumar TV, Wound healing potential of scaffolds prepared from porcine jejunum and urinary bladder by a non detergent/enzymatic method, Journal of Biomaterial Applications, 2015, 29(9):1218-29, http://www.ncbi.nlm.nih.gov/pubmed/25425562
4. Revi, D, Vineetha VP, Muhamed J, Rajan A, Anilkumar TV, Porcine cholecyst–derived scaffold promotes full-thickness wound healing in rabbit, Journal of Tissue Engineering, 2014,   18;4, http://tej.sagepub.com/content/4/2041731413518060.long
5. Revi D, Paul W, Anilkumar TV, Sharma CP, Chitosan Scaffold Co-cultured with keratinocyte and fibroblast heals full thickness skin wounds in rabbit, Journal of Biomedical Materials Research Part-A, 2014, 102(9):3273-81., http://onlinelibrary.wiley.com/doi/10.1002/jbma.35003/abstract
6. Anilkumar TV, Vineetha VP, Deepa R, Jaseer M, and Akhila R, Biomaterial properties of cholecyst-derived-scaffold recovered by a non-detergent/ enzymatic method, Journal of Biomedical Materials Research Part-B-Applied Biomaterials, 2014, 102B,7; , http://onlinelibrary.wiley.com/doi/10.1002/jbm.b.33131/epdf
7. Sini S, Latha PG, Anilkumar TV, Suja SR, Gopa, Raj, K.B. Rameshkumar KB, Shyamal S, Shine VJ, Anuja GI, Shikha P, Krishnakumar NM, Sreejith G, Rajasekharan S, Safety assessment of tuberous rhizome of, Global Journal of Pharmacology, 2014, 8 (2): 128-139, http://www.idosi.org/gjp/8(2)14/2.pdf
8. Manju Alex, M V Sauganth Paul, M Abhilash, Varghese V Mathews, TV Anilkumar and R Harikumaran Nair, Astaxanthin modulates, British Journal of Urology International, 2014, 114(3):458-66, http://onlinelibrary.wiley.com/doi/10.1111/bju.12537/abstract
9. Revi D, Willi Paul, Anilkumar TV Chandra P. Sharma, Differential healing of full thickness rabbit skin wound by fibroblast loaded chitosan sponge, Journal of Biomaterials and Tissue Engineering, 2013, 0.125, www.ingentaconnect.com/content/asp/jbte/2013/00000003/.../art00002
10. Jaseer Muhamed, Deepa Revi, Roy Joseph, Anilkumar T, Phenotypic modulation of cell types around implanted polyethylene terephthalate fabric in rabbit muscle, Toxicologic Pathology, 2013, 41(3): 497-507, http://tpx.sagepub.com/content/41/3/497.long
11. Nampi PP, Kartha CC, Jose G, Anilkumar PR, Anilkumar T, Varma, H.K, Solgel nanoporous silica as substrate for immobilization of conjugated biomolecules for application as fluorescence resonance energy transfer (FRET) based biosensor, Sensors and Actuators B: Chemical, 2013, 185: 252-257, http://www.sciencedirect.com/science/article/pii/S0925400513005005
12. Kumar PT Sudheesh, VK Lakshmanan, Anilkumar TV, C Ramya, P Reshmi, AG Unnikrishnan, SV Nair, J Rangasamy, Flexible and micro-porous chitosan hydrogel/nano ZnO composite bandages for wound dressing: in vitro and in vivo evaluation, ACS Applied Material and Interfaces, 2012, 4 (5): 2618-29., http://pubs.acs.org/doi/pdf/10.1021/am300292v
13. Anilkumar TV, Muhammed J, Jose A, Jyothi A, Mohanan PV and Lissy KK, Advantages of hyaluronic acid as a component of fibrin sheet for care of acute wound, Biologicals, 2011, 1.625, http://www.sciencedirect.com/science/article/pii/S1045105611000169
14. Swathy SS; Anilkumar TV, Healing response of skeletal muscle to implanted biomaterials in rabbit: an immunohistochemical study of desmin and alpha-smooth-muscle-actin positive cells, Indian Journal of Veterinary Pathology, 2008, 31 (2): 113-119
15. Burugapalli K, Anilkumar T(joint first author), Chan JC, Yao L, Brody S, Kelly JL, Pandit A, Scaffold with a natural mesh-like architecture: isolation, structural, and in vitro characterization, Biomacromolecules, 2007, 8(3): 928-936, http://pubs.acs.org/doi/pdfplus/10.1021/bm061088x
16. Nishi KK, Antony M, Mohanan PV, Anilkumar TV, Loiseau PM, Jayakrishnan A, Amphotericin B-gum Arabic conjugates: synthesis, toxicity, bioavailability and activities against, Pharmaceutical Research, 2007, 24(5): 971-80, http://link.springer.com/article/10.1007%2Fs11095-006-9222-z
17. Anilkumar TV, Shelma R, Joseph R, Mohanan, PV, Muraleedharan CV, Implant Pathology of polyvinylidene fluoride coated polyethylene tetrathalate fabric in rabbits, Indian Journal of Veterinary Pathology, 2007, 31 (1): 11-16., http://www.indianjournals.com/ijor.aspx?target=ijor:ijvp&volume=31&issue=1&article=002
18. S. Brody, TV Anilkumar, Liliensiek S, Last JA, Murphy CJ and A. Pandit, Characterizing nanoscale topography of the aortic heart valve basement membrane for tissue engineering heart valve scaffold design, Tissue Engineering, 2006, 12(2): 413-421, http://online.liebertpub.com/doi/pdf/10.1089/ten.2006.12.413
19. Breen A; Strappe P, Anil Kumar, O’ Brien T, Pandit A, Optimisation of a Fibrin Scaffold for Sustained Release of an Adenoviral Gene Vector, Journal of Biomedical Biomaterials Research, 2006, 78(4): 702-708., http://onlinelibrary.wiley.com/doi/10.1002/jbm.a.30735/epdf
20. S. Velayudhan, TV Anilkumar, TV Kumary, PV Mohanan, AC Fernandez, HK Varma, P Ramesh, Biological evaluation of pliable hydroxyapatite-ethylene vinyl acetate co-polymer composite intended for cranioplasty, Acta Biomaterialia, 2005, 4.1666666666666664E-2, http://www.sciencedirect.com/science/article/pii/S1742706104000297
21. R Rajendran, SP Twinkle, TV Anikumar J Annie, Cell death does not herald epithelial involution (" atrophy") in oral sub mucous fibrosis: a TEM study, Indian journal of dental research: official publication of Indian Society for Dental Research, 2003, 15(1): 13-19, http://www.sciencedirect.com/science/article/pii/S1742706104000297
22. Mohanty M, Anilkumar TV, Mohanan PV, Muraleedharan CV, Bhuvaneshwar GS, Derangere F, Sampeur Y, Suryanarayanan R., Long term tissue response to titanium coated with diamond like carbon, Biomolecular Engineering, 2002, 0.79166666666666663, http://www.sciencedirect.com/science/article/pii/S1389034402000266
23. Anil Kumar PR, Bindu Menon, Anilkumar TV, Kumari TV, Culture of neonatal rat liver cells: a preliminary observation, Trends in Biomaterials and Artificial Organs, 2002, 16(1) 34-37., http://medind.nic.in/taa/t02/i1/taat02i1p34.pdf
24. Ryan CJ, Anilkumar T, Aslam M, Ben-Hamida AJA, Khorsandi SE, Pusey CD, gaylor JDS, Courtney JM., Multisorbent plasma perfusion in fulminant hepatic failure: effects of duration and frequency of treatment in rats with grade III hepatic coma, Artificial organs, 2001, 1.0416666666666667, http://onlinelibrary.wiley.com/doi/10.1046/j.1525-1594.2001.025002109.x/abstract
25. M Alison, M Golding, V Emons, T Anilkumar, C Sarraf, Stem cells of the Liver, Medical Electron Microscopy, 1999, 31(2): 53-60, http://link.springer.com/article/10.1007%2FBF01557781#page-1
26. Anilkumar T, Ryan CJ, Aslam M, Poulsom R Alison M, The anti proliferative effect of plasma from rats with acute fulminant hepatic failure, Scandinavian Journal of Gastroenterology, 1997, 32: 1152-61, http://www.tandfonline.com/doi/abs/10.3109/00365529709002996?journalCode=igas20
27. Ravirajan CT, Sarraf CE, Anilkumar TV, Golding MC, Alison MR, Isenberg DA, An analysis of apoptosis in lymphoid organs and lupus disease in murine systemic lupus erythematosus (SLE)., Clinical and Experimental Immunology, 1996, 105(2): 306-312, http://www.readcube.com/articles/10.1046%2Fj.1365-2249.1996.d01-770.x
28. Lalani EN, Golding M, Hudson M, Chieffi G, Stamp G, Anilkumar TV, Sarraf C, Alison MR, Protein extraction and western blotting from methacarn-fixed tissue, Journal of Pathology, 1995, 177(3): 323-328., http://www.ncbi.nlm.nih.gov/pubmed/8551396
29. Golding M, Sarraf CE, Lalani EN, Anilkumar TV, Edwards RJ, Nagy P, Thorgeirsson SS, Alison MR, Oval cell differntiation into hepatocytes in the acetylaminofluorene-treated rat liver, Hepatology, 1995, 22: 1243-1253., http://www.ncbi.nlm.nih.gov/pubmed/7557877
30. Anilkumar TV, Golding M, Edwards RJ, Lalani EN, Sarraf CE, Alison MR, The resistant hepatocyte model of carcinogenesis in the rat: the apparent independent development of oval cell proliferation and early nodules, Carcinogenesi, 1995, 16: 845-853, http://www.ncbi.nlm.nih.gov/pubmed/7728966
31. Anilkumar TV, Voigt RP, Quigley PJ, Krausz T, Sarraf CE & Alison MR, Squamous cell carcinoma of the feline thymus with widespread apoptosis, Research in Veterinary Sciences, 1994, 56: 208-215, http://www.ncbi.nlm.nih.gov/pubmed/8191012
32. Sarraf CE, Lalani EN, Golding M, Anilkumar TV, Poulsom R, Alison MR, Cell behaviour in the acetylaminofluorene treated regenerating rat liver: Light and electron microscopic observations, American Journal of Pathology, 1994, 145: 1114-1126, http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1887432/pdf/amjpathol00059-0140.pdf
33. Alison MR, Poulsom R, Jeffery R, Anilkumar TV, Jagoe R, Sarraf CE., Expression of Hepatocyte Growth Factor mRNA activation in the rat liver, Journal of Pathology, 1994, 171: 291-299, http://onlinelibrary.wiley.com/doi/10.1002/path.1711710410/abstract
34. Nasim MM, Anilkumar TV, Sarraf CE. Alison MR, Transforming growth factor immunoreactivity in a variety of epithelial tissues, Cell Proliferation, 1993, 26: 449-460, http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2184.1993.tb00132.x/abstract
35. Anilkumar TV, Sarraf CE, Alison MR, Biology and Pathology of programmed cell death (apoptosis)., Veterinary and Human Toxicology, 1992, 34: 251-254, http://www.ncbi.nlm.nih.gov/pubmed/1609501
36. Anilkumar TV, Sarraf CE, Hunt T, Alison MR, The nature of cytotoxic drug-induced cell death in murine intestinal crypts, British Journal of Cancer, 1992, 65: 552-558, http://www.ncbi.nlm.nih.gov/pubmed/1562464
37. Anilkumar TV, Sandhyamani S, Atrial septal defect in a bonnet monkey, Journal of Medical Primatology, 1990, 19:749-752., http://www.ncbi.nlm.nih.gov/pubmed/2084263
38. Anilkumar TV, Rajan A, Immunopathological response of goats in aflatoxicosis, Indian Journal of Animal Sciences, 1987, 57: 817-822