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Dr. Manoj G.

2573 MANOJ

Contact Information

Address:

Dr. Manoj G.
Scientist 'E'
कृत्रिम आंतरिक अंगों का प्रभाग

Phone number:

1319(O)

People - Division of Artificial Internal Organs

Dr. Manoj G.

Academic Qualifications

  • Ph.D (Genetics), Osmania University, 2010
  • MSc Biotechnology, Bharathidasan University, 2005
  • BSc Biotechnology, Kerala University, 2002

Professional Record

  • Scientist E, Biomedical Technology Wing, SCTIMST, Jan-22 to Till date
  • Scientist-D, Biomedical Technology Wing, SCTIMST, Aug 2018 to Jan-2022
  • Scientist E-2, Corporate Research and Development Centre (CRDC), HLL Lifecare Ltd, Aug 2016- Aug 2018
  • Scientist E-1, Corporate Research and Development Centre (CRDC), HLL Lifecare Ltd, Mar 2012 to Aug 2016
  • Assistant Professor, Aurora’s Technological & Research Academy, Hyderabad, Aug 2010 to Feb 2011

Awards

  • Received gold medal award from HLL Lifecare Limited for "Outstanding contribution to the innovation and R&D efforts" at CRDC, HLL in Aug, 2014
  • Best Paper award in 49th conference of Indian Society of Gastroenterology ISGCON& APDW), New-Delhi, 2008. "Rapid Molecular Assay for the diagnosis of Clarithromycin resistant H. pylori directly from human gastric biopsies-- An approach to design antibiotic regimen.
  • Presidential poster/Paper award in 47th conference of Indian Society of Gastroenterology (ISGCON), Mumbai, 2006. "A Simple and Novel Multiplex PCR assay for diagnosing and genotyping H. pylori infection from human gastric biopsies".

Area of Interest

  • Mutational screening, Genome Analysis, Assay development, Biomarker studies
  • Quality by design (QbD) and development of In-vitro diagnostic devices (IVDs) such as Immunochromatographic, ELISA and other point of care devices etc.
  • Benchside to bedside evaluations of laboratory developed prototypes of medical device & IVDs as per standard guidelines
  • Pilot productions, plant trials & Technology transfer of In-vitro diagnostic devices and medical devices (IVDs).

Collaboration

  • M/s. Vinvish Technologies PVT. Ltd, Trivandrum, India
  • M/s. VST ioT Solutions, Kochi, India
  • Rajiv Gandhi Centre for Biotechnology, Trivandrum, India
  • M/s. Biogeniex Inc. In, Lucknow, India
  • M/s. Origin Diagnostics and Research Centre, Kerala, India
  • M/s. HLL Lifecare Limited, Trivandrum, India, kerala

Current Activities

  • PhD supervisor, Teaching and Program Coordinator for SROP and PhD Curriculum Activities
  • Involved in the development and clinical validations of In-vitro diagnostic devices & medical devices

पेटेंट

  • A kit for the rapid detection of COVID-19 IgG/IgM antibodies using Immunochromatographic techniques (Filed)
  • A rapid detection test kit for Chlamydia trachomatis and the process thereof (Filed)
  • A test kit for the determination of PCT and the process thereof (Filed)

Fellowships

  • Received Fast Track proposal for young scientists from DST, India in 2012

Membership

  • Society for Biomaterials and Artificial Organs, India (SBAOI)
  • Material Research Society of India (MRSI)

On-going Projects

  • NT-proBNP Quantitative kit for Heart failure
  • Rapid test kit (Immunochromatographic based)- Chlamydia Antigen Diagnosis
  • Rapid test kit (Immunochromatographic based)- Sepsis Diagnosis
  • Testing and benchmarking studies of Medical devices & IVD (Industry funded)

Organisational Activities

  • Department Coordinator
  • PhD Course Co-Ordinator

Team

  • कृत्रिम आंतरिक अंगों का प्रभाग

No. of Publications

  • 18

Dissertations Supervised - M.Tech

  • 2

Technology Transferred

  • Rapid test kit IgG/IgM SARS CoV-2

प्रकाशन

Article

  1. Jagan A, Ozhiparambil; Manoj, G; Jayaprakash, Natamai; Ramesh, M Nair; Sara Chandy, Molecular Diversity of Hepatitis B Virus X gene in central Kerala, Southern India, Journal of Clinical and Diagnostic Research, 2018, DC10-14, https://www.jcdr.net/article_abstract.asp?issn=0973-709x&year=2018&month=June&volume=12&issue=6&page=DC10-DC14&id=11572
  2. Manoj, G; Amrutha, C; Rajmohan, G; Sunil Bhasker; Rajeev, A; Abi Santhosh Aprem, A Feedback Survey On the Clinical Performance and Acceptability of a Long-Term Levonorgestrel Releasing Intrauterine System (EMILY), International Journal of Scientific Reports, 2018, 4(7):186-191, http://www.sci-rep.com/index.php/scirep/article/view/444
  3. Regidi, S; Ravindran, S; Vijayan, AL; Maya, V; Sreedharan, L; Varghese, J; Ramaswami, K; Manoj G, Effect of lyophilization on HRP-antibody conjugation: an enhanced antibody labeling technology, BMC Res Notes, 2018, 11(1):596, https://www.ncbi.nlm.nih.gov/pubmed/30124170
  4. Pillai, LS; Regidi, S; Varghese, SD; Ravindran, S; Maya, V; Varghese, J; Ramaswami, K; Gopimohan, R; Manoj, G, Nonhormonal selective estrogen receptor modulator 1-(2-[4-{(3R,4S)-7-Methoxy-2, 2-dimethyl-3-phenyl-chroman-4yl}phenoxy]ethyl)pyrrolidine hydrochloride (ormeloxifene hydrochloride) for the treatment of breast cancer, Drug Dev Res., 2018, 79(6):275-286, https://www.ncbi.nlm.nih.gov/pubmed/30284735
  5. Lakshmi, S; Sandra, S; Rahul, BS; Saikant, R; Vani Maya, Manoj, G; Padmaja, G; Remani, P, In-vitro and in-vivo studies of 5,7 dihydroxy flavones isolated from Alpinia galanga (L.) against human lung cancer and ascetic lymphoma, Med. Che. Res, 2018, 10.1007/s00044-018-2260-3, In press
  6. Saikanth, R; Shilpa, Ravindran; Ashitha, Vijayan; Vani, Maya; S, Lakshmi; R, Kartik; Manoj, G, Resonse of letter to the editor on Procalcitonin: a promising diagnostic marker for sepsis and antibiotic therapy, Journal of intensive care, 2017, 5:58:00 AM, https://www.ncbi.nlm.nih.gov/pubmed/29234495
  7. Ashitha L. Vijayan; Vanimaya; Shilpa, Ravindran; R, Saikant; S, Lakshmi;R, Kartik; Manoj. G, Procalcitonin: a promising diagnostic marker for sepsis and antibiotic therapy, Journal of Intensive Care, 2017, 5:51:00 AM, https://www.ncbi.nlm.nih.gov/pubmed/28794881
  8. Anumol, Mathew; Sumitha, CK; Atul, PV; Seema, Oommen; Manoj, G, HBx Gene Mutations in Hepatitis B Virus and Hepatocellular Carcinoma, Gastroenterology Res., 2014, 7(1):1-4, https://www.ncbi.nlm.nih.gov/pubmed/27785261
  9. Sivaram, G; Tiwari, SK; Bardia, A; Manoj, G; Santhosh, B; Saikant, R; Aejaz, H; Vishnupriya, S; Khan, AA; Habibullah C., Association of genetic variants of mannan-binding (MBL) lectin-2 gene, MBL levels and function in ulcerative colitis and Crohn's disease, Innate Immun, 2011, 17(6):526-31, https://www.ncbi.nlm.nih.gov/pubmed/21088049
  10. Sri Krishna, V; Uday, Kiran M; Siva, Rama Prasad; Anusha, G; Mohana, Rao; Manoj, G., Homology modeling and ligand interaction of human trafficking protein particle complex subunit 3-like protein and its correlation with Alzheimer?s disease, Journal of medical and Allied Sciences, 2011, 1(1) 21-24, http://www.scopemed.org/?mno=210075
  11. Santosh, KT; Vishwas, Sharma; Varun, KS; Manoj, G; Saikant, R; Amrita, Nandan; Avinash, Bardia; Sivaram, Gunisetty; Md. Aejaz Habeeb; Aleem Khan; CM Habibullah, Phylogenetic analysis based on EPIYA repeats in the cagA gene of Indian Helicobacter pylori, and the implications of sequence variation in tyrosine phosphorylation motifs on determining the clinical outcome, Genetics and Molecular Biology, 2011, 34 (1) 1415-4757, https://www.ncbi.nlm.nih.gov/pubmed/21734830
  12. Santhosh, Kumar B; Santosh K, Tiwari; Manoj, G; Zakia, Abid; Adeel, Ahmad; Amit, Kunwar; Aleem A, Khan; K, Indira Priyadarsini, Anti-ulcer and antimicrobial activities of sodium selenite against Helicobacter pylori: in vitro and in vivo evaluation, Scandinavian Journal of Infectious Diseases, 2010, 42(4):266-74, https://www.ncbi.nlm.nih.gov/pubmed/20092379
  13. Santosh, Tiwari; Manoj, G; Sivaram, G; Vishwas, Sharma; Saikant, R; Md. Aejaz, Habeeb; Zakia, Abid; Aleem A, Khan; CM, Habibullah, Relevance of genotypes of Helicobacter pylori in gastric pathology and its correlation with plasma malondialdehyde and nitric oxide levels, Inflammopharmacology, 2010, 18 (2): 59-64, https://www.ncbi.nlm.nih.gov/pubmed/20143166
  14. Santhosh, KB; Santosh, KT; R, Saikant; Manoj, G; Amit, Kunwar; G, Sivaram; Zakia, Abid; Adeel, Ahmad; Indira, Priyadarsini; Aleem A Khan., Antibacterial and ulcer healing effects of organoselenium compounds in naproxen induced and Helicobacter pylori infected Wistar rat model, Journal of Trace Elements in Medicine and Biology, 2010, 24 (4) 263-270, https://www.ncbi.nlm.nih.gov/pubmed/20678908
  15. Tiwari, SK; G, Manoj; Khan, AA; Habeeb, A; Habibullah CM., Chronic idiopathic thrombocytopenia purpura and Helicobacter pylori eradication: A case study, Gastroenterology Research, 2009, 2: 57-59, https://www.ncbi.nlm.nih.gov/pubmed/27956954
  16. Santosh K, Tiwari; Manoj, G; Prashant, M; Mohammed Aejaz, Habeeb; Aleem A, Khan; Habibullah, CM, Simplified and Versatile method for bisulphite based DNA methylation analysis using small quantity of human saliva and gastric biopsies, Journal of Clinical Laboratory Analysis, 2009, 23(3): 172-174, https://www.ncbi.nlm.nih.gov/pubmed/19455637
  17. Manoj, G; Santosh K, Tiwari; Vasanth, Kumar G; Sharma, V; Syed Ibrahim Hassan; Prabhakar, B; Uma, Devi; Kiran, Kumar; Shakeel, Ahmed; Zakia, Abid; Mohammed, Aejaz Habeeb; Aleem A,Khan; Habibullah CM, Prognostic significance of genotyping Helicobacter pylori infection in patients in younger age groups with gastric cancer, Postgraduate Medical Journal, 2008, 84(990):193-7, https://www.ncbi.nlm.nih.gov/pubmed/18424576
  18. Manoj, G; Santosh, K. Tiwari; Shakeel, Ahmed; Sharma, V; Sivaram, G; Zakia, Abid; Mohammed, Aejaz Habeeb; Aleem A, Khan; Habibullah, CM, Association of Helicobacter pylori Restriction Endonuclease-replacing Gene, hrgA with overt gastrointestinal diseases, Arquivos de Gastroenterologia, 2008, 45(3): 225-229, https://www.ncbi.nlm.nih.gov/pubmed/18852951
  19. Santosh K, Tiwari; Aleem A, Khan; Manoj, G; Shakeel, Ahmed; Zakia, Abid; Aejaz, Habeeb; CM Habibullah, A simple multiplex PCR assay for diagnosing virulent Helicobacter pylori infection in human gastric biopsy specimens from subjects with gastric carcinoma and other gastro-duodenal diseases, Journal of Applied Microbiology, 2007, 103(6): 2753-2760, https://www.ncbi.nlm.nih.gov/pubmed/17850305

Case Report

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