Dr. Dinoop K. P.

Academic Qualifications

• Diplomateship (Medical Microbiology) - Royal College of Pathologists (FRCPath Part 1), London, United Kingdom: 2023
• Associateship (Medical Microbiology) - Royal College of Pathologists (FRCPath Part 1), London, United Kingdom: 2013
• D.N.B. (Microbiology) - National Board of Examinations (NBE), India: 2013-14
• M.D. (Microbiology) - Jawaharlal Institute of Postgraduate Medical Education & Research (JIPMER), Pondicherry, India: 2012
• M.B.B.S. - Pondicherry Institute of Medical Sciences (PIMS), Pondicherry, India: 2009

Professional Record

• Additional Professor (Clinical Microbiology) - Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST): January 2025 - Current date
• Associate Professor (Clinical Microbiology) - Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST): January 2022 - December 2024
• Assistant Professor (Clinical Microbiology) - Sree Chitra Tirunal Institute for Medical Sciences & Technology (SCTIMST): August 2018 - December 2021
• Assistant Professor (Microbiology) - PSG Institute of Medical Sciences and Research (PSGIMSR): January 2015 - August 2018
• Senior Resident (Microbiology) - Jawaharlal Institute of Postgraduate Medical Education & Research (JIPMER): December 2012 - December 2014

Awards

• European Society of Clinical Microbiology and Infectious Diseases (ESCMID) observership grant 2022 - Awarded observership grant to visit to Antimicrobial Resistance and healthcare associated infections (AMRHAI) unit of UK Health Security Agency (UK-HSA), Colindale, London
• Young Researcher Award in Clinical Microbiology - 4th Venus International Healthcare Awards (VIHA), 2021
• Associateship award (Medical Microbiology) - Royal College of Pathologists, London, United Kingdom
  Membership - National academy of Medical Sciences (MNAMS)
  Best research paper award: IATP National conference (TROPACON 2011: GMC, Nagpur)- Evaluation of real-time PCR in diagnosis of amoebic liver abscess
  Invited Chairperson/Judge for postgraduate (M.D. Microbiology) poster presentation sessions in 2 national conferences: MICROCON 2015 - JIPMER & TROPACON 2016 - JIPMER
  2 Quiz Prizes in IAMM National Conferences
  First Prize - 36th IAMM Conference Quiz (2012) - LHMC, New Delhi
  Second Prize - 34th IAMM Conference Quiz (2010) - Kolkata
  

Area of Interest

• Clinical Microbiology
  Infection Prevention and Control
  Diagnostic Stewardship
  Antimicrobial Stewardship
  Clinical & Translational research in cardiovascular and neuroinfectious diseases.

Current Activities

• Patient care (Infectious diseases diagnosis and management)
  Research (Clinical and Translational)
  Member - Hospital Infection Control Committee (HICC)
  Member - Infection Control Team (ICT)
  Laboratory Quality Management
  Teaching and training
• Administrative activities (Biosafety officer, GeM verification officer)

पेटेंट

• Patents filed (Indian): Rapid detection of COVID-19 antigens using immunochromatographic technique Patent reference no: IPCOV172.Y20; Application no: 202041015199 dated 07.04.2020
• Patent filed (Indian): Rapid detection of COVID-19 IgG/IgM antibodies using immunochromatographic technique. Patent reference no: IPCOV173.Y20; Application number: 202041015212 dated 07.04.2020
• Patent filed (Indian): A test kit for the determination of procalcitonin (PCT) and the process thereof. Patent reference no: IPAIO197.Y20; Application no: 202041043487 dated 06.10.2020
• Patents filed (Indian): A rapid detection kit for Chlamydia trachomatis and the process thereof. Patent reference no: IPAIO0203.Y20. Application no: 202041053682 dated 10.12.2020

Membership

• Member (Diplomate) - Royal College of Pathologists (RCPath), London, UK
  Member - European Society of Clinical Microbiology and Infectious Diseases (ESCMID)
  Member - American Society of Microbiology (ASM)
  Member - National Academy of Medical Sciences (MNAMS)
  Life member - Indian Medical Association
  Life member - Indian Association of Medical Microbiologists (IAMM)
  Life member - Indian Academy of Tropical Parasitology (IATP)
  Life member - Academy of Clinical Microbiologists (ACM)

On-going Projects

• Principal Investigator (PI): Development of 2nd generation Chitra SARS-CoV2/Flu/RSV multiplex RT-PCR kit for detection of treatable respiratory viral pathogens: Proof of concept, SCTIMST Technology Development Fund (TDF): Rs. 9.7 lakhs; July 2024 - June 2025
• Co-Investigator (Co-I): An isothermal platform-based fever panel for the detection of tropical fever etiology, Funded by DST-TRC: Rs. 24.5 lakhs; February 2024 - July 2025
• Co-Investigator (Co-I): Rapid detection of viable pathogenic bacteria using nanosensors, Funded by DST-TRC: Rs. 10.6 lakhs: February 2024 - January 2026
• Co-Investigator (Co-I): Setting up of Nation-wide Network of Laboratories for Managing Epidemics and National Calamities (Viral Research and Diagnostic Laboratory – Medical College level) at SCTIMST, Funded by ICMR, Govt. of India: Rs. 3.8 crores: 2024-2029

Projects Completed

• Principal Investigator (PI): A prospective cohort study on cerebrospinal fluid (CSF) diversion catheter-related infections in a tertiary referral neurosurgical care center, Funded by ICMR, Govt. of India: Rs. 21.29 lakhs: October 2020 - September 2022
• Principal Investigator (PI): Role of novel Biomarkers and clinical Scoring systems in predicting progression to Sepsis in infected post-Cardiac Surgery patients, Funded by ICMR (Rs. 8.7 lakhs) & SCTIMST (Rs. 4.7 lakhs): 2021-2023
• Clinical Principal Investigator (PI): Point-of-care device for sepsis management (Procalcitonin - based) - Technical Research Centre (TRC) Department of Science & Technology (DST): Rs. 40 lakhs; 2020 - 2023

Training

• Liverpool Neurological Infectious Diseases Course (Neuro ID Virtual course 2021) - University of Liverpool (Brain Infections Group)

Organisational Activities

• Treasurer: 9th Triennial Conference of the Academy of Clinical Microbiologists (9th ACM TRICON 2023): co-organised by GMC, RCC and SCTIMST, Thiruvananthapuram – 30th September to 2nd October 2023
• Organising Secretary: Clinical Microbiology and Infectious Diseases (CMID 2020): co-organised by SCTIMST and ACM (Academy of Clinical Microbiologists) - February 2020
• Organising Secretary: CME on Infection Prevention and Control (IPC) in a superspecialty setting - Facing the future (SCTIMST) - March 2019

Team

• Hospital Infection Control Committee (HICC)
• Infection Control Team (ICT)
• Comprehensive Neuro-Intensive Care Team

Books and Journals edited

• Editorial Board member (Assistant Editor) - Opinions in Medical Sciences, Technology and Health (OMSTH) [Journal publication of SCTIMST]: 2022-2025
• Editorial Board member (Assistant Editor) - Journal of The Academy of Clinical Microbiologists (JACM): 2020 - 2023
• Editorial Board member (Assistant Editor) - Tropical Parasitology: 2013-2018

Invited talks

• International Brain Research Organisation - Asia Pacific Regional Committee (IBRO-APRC 2019): Role of Brain-Gut-Microbiome axis in neurological disorders: Emerging trends; organised by IBRO and SCTIMST
• Triennial conference of the Academy of Clinical Microbiologists (ACM – TRICON 2023): Talk on “Designing and implementing an evidence-based care bundle for prevention of post-neurosurgery device-associated ventriculitis/meningitis” organized by the Academy of Clinical Microbiologists (ACM).
• State Chapter conference of the Indian Association of Medical Microbiologists (IAMM) – PSG MICROCON 2024: Talk on “Unravelling Antimicrobial Resistance among Gram-negative Bacilli”

Reviewer

• PLOS Neglected Tropical Diseases, Journal of Infection and Chemotherapy, Diagnostic Microbiology and Infectious Diseases, Indian Journal of Medical Microbiology, Journal of the Academy of Clinical Microbiologists, International Journal of Advanced Medical Research.

प्रकाशन

Article

1. Dinoop K Ponnambath, Ganesh Divakar, Jincy Mamachan, Shiny Biju, Kavita Raja, Mathew Abraham, Development of an Evidence-based Care Bundle for Prevention of External Ventricular Drain-related Infection: Results of a Single-center Prospective Cohort Study and Literature Review, Indian Journal of Critical Care Medicine, 2024, 28(8):760-768
2. Dinoop Korol Ponnambath, Ganesh Divakar, Jincy Mamachan, Shiny Biju, Kavita Raja, Mathew Abraham, Epidemiology, clinical profile, and outcomes of CSF-diversion catheter-related infections – Prospective cohort study results from a single quaternary neurosurgery referral centre, Indian Journal of Medical Microbiology, 2024, Mar-Apr;48:100534.
3. Jyothi Embekkat Kaviyil, Kavita Raja, Rakhal Gaitonde, Sreekumar Easwaran, Kumari Kala V, Dinoop Korol Ponnambath, Targeted Sanger Sequencing of a Cluster of COVID-19 Cases in the Surgical ICU of a Non-COVID Hospital: Lessons Learned, Cureus, 2023, Sep 5;15(9):e44755.
4. Raja K, Ponnambath DK, Kaviyil JE, Biju S, Impact of a single intervention as part of a antimicrobial stewardship in a surgical unit of a tertiary-care referral center for neurosurgery, Antimicrobial Stewardship and Healthcare Epidemiology, 2023, 3(1):S1, DOI: 10.1017/ash.2023.4
5. Ponnambath DK, Khimji PB, Kaviyil JE, Raja K, Abraham M, Thomas B., A Rare Case Of Cerebellar Abscess Due To Listeria monocytogenes In An Elderly Patient With Ulcerative Colitis, Neurology India, 2022, 70:1692-3
6. Raja K, Mukhopadhyay C, Shetty AK, Chinnan JP, Sudarsana J, Ponnambath DK, et al. , Detection and reporting of Carbapenemase producing Gram negative bacilli in Clinical Microbiology: A survey of practices in laboratories across India, J Acad Clin Microbiol , 2022, 24(2):55-62
7. Ponnambath DK, Kaviyil JE, Raja K, Kesavapisharady K, Thomas B, Narasimhaiah D, Sehgal R, Kaur U, An unusual guest in an unusual location of the brain of a rural tribal man, J Acad Clin Microbiol , 2022, 24:44-7
8. Kaviyil JE, Ponnambath DK, Sasidharan B, Vidyadharan P, Raja K, Aggregatibacter aphrophilus, a HACEK group pathogen as a cause of prosthetic valve endocarditis, J Acad Clin Microbiol , 2022, 24:41-3
9. Lotlikar R, Menon RN, Thomas B, Poyuran R, Narasimhaiah D, Ponnambath DK, MOG‐Antibody Mediated Clinically Isolated Syndrome after COVID‐19 in a Post Partum Woman‐ A Veritable ‘Double Hit’!, Neurology India, 2022, 70:1281‐2
10. Sundaram S., Ponnambath D.K., Nair S.S. , Microbiota-Gut-Brain Axis in Neurological Disorders, Human Microbiome. Springer, Singapore, 2022, In: Thomas S. (eds)
11. Rosenthal V D, Duszynska W, Ider B, Raja K, Ponnambath DK, S Biju et al, International Nosocomial Infection Control Consortium (INICC) report, data summary of 45 countries for 2013-2018, Adult and Pediatric Units, Device-associated Module, American Journal of Infection Control, 2021, S0196-6553(21)00272-8, 10.1016/j.ajic.2021.04.077
12. Ponnambath DK, Gopalakrishnan A, Pillai VV, Kaviyil JE, Raja K., Clinical Profile of Prosthetic Valve Endocarditis due to Candida parapsilosis: A 11-year Retrospective Observational Study from a Quaternary Cardiac Referral Institute in India, Indian Journal of Critical Care Medicine, 2021, 25(8):860-865, 10.5005/jp-journals-10071-23915
13. Pavankumar Rudrabhatla, Sruthi S. Nair, Jithin George, Sabarish Sekar, Dinoop Korol Ponnambath, Isolated Myelitis and Intramedullary Spinal Cord Abscess in Melioidosis - A Case Report, The Neurohospitalist, 2021, , https://doi.org/10.1177/19418744211025386
14. Poyuran R, Ponnambath DK, Vilanilam GC, Chandrasekharan K, Narasimhaiah D, Mycobacterial spindle cell pseudotumour of the brain in an immunocompetent adult, पैथोलॉजी, 2021, S0031302521000799
15. Maya V, Kaviyil JE, Ponnambath DK, Nair RP, Bhatt A, Pilankatta R, et al, Evaluation of diagnostic accuracy of developed rapid SARS-COV-2 IgG antibody test kit using novel diluent system., Virus disease, 2021, 1-7
16. Raja K, Kaviyil JE, Ponnambath DK, Biju S, Containment of COVID-19 outbreaks in a non-COVID hospital – An experience;, J Acad Clin Microbiol, 2021, 23:34-7
17. Bhattacharya S, Joy V M, Goel G, Nath S R, Raja K, Ponnambath D K et al, Antimicrobial stewardship programme from policies to practices: A survey of antimicrobial stewardship programme practices from 25 centres in India, J Acad Clin Microbiol, 2019, 21(1):4-9, 10.4103/jacm.jacm_17_19
18. Mathew RR, Ponnambath DK, Mandal J, Roy G, Enteric Pathogen profile and Knowledge, Attitude and Behaviour about food hygiene among food handlers in a tertiary health care center, International Journal of Medicine and Public Health, 2019, 9(3):60-65, 10.5530/ijmedph.2019.3.16
19. Ponnambath DK, Khimji PB, Kaviyil JE, Raja K, Vilanilam GC, Thomas B., First report of intracranial epidermoid cyst infection and brain abscess caused by Salmonella Paratyphi A, J Acad Clin Microbiol, 2019, 21:85-88, 10.4103/jacm.jacm_31_19
20. Kaviyil JE, Pitchai S, Ponnambath DK, Raja K, A rare case of mycotic aneurysm due to Salmonella Enteritidis, J Acad Clin Microbiol, 2019, 21:94-96, 10.4103/jacm.jacm_27_19
21. Hassan H, Ponnambath DK, Raja K, Post-operative infective endocarditis with aortic root abscess due to Mycobacterium abscessus, J Acad Clin Microbiol, 2019, 21:89-93, 10.4103/jacm.jacm_28_19
22. Ponnambath DK, Priyadharshini M, Boppe A, Non Lactational Breast Abscess due to Actinomyces odontolyticus: First Case Report from Asia, J Clin Diagn Res, 2018, 12(4): DD01-03, http://www.jcdr.net/article_abstract.asp?issn=0973-709x&year=2018&month=April&volume=12&issue=4&page=DD01-DD03&id=11354
23. Parija SC, Mandal J, Ponnambath DK, Halder A, Ethical Dilemmas and Etiquettes of Scientific Publication, Writing and Publishing a Scientific Research Paper, 2017, 185-195, https://books.google.co.in/books?id=tLQuDwAAQBAJ&pg=PA189&lpg=PA189&dq=Ethical+Dilemmas+and+Etiquettes+of+Scientific+Publication.+Writing+and+Publishing+a+Scientific+Research+Paper.+Singapore:+Springe
24. Mandal J, Ponnambath DK, Parija SC, Ethics of translational medical research, Trop Parasitol, 2017, 2017;7(2):62-4., https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652056/
25. Mandal J, Ponnambath DK, Parija SC, Bioethics: A brief review, Trop Parasitol, 2017, 7(1):5-7, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369276/
26. Dinoop KP, Swaran KM, Appalaraju B, Karthikeyan S, Clinico-mycological and antifungal susceptibility profiles of candiduria in a tertiary care hospital from South India., Nat J Lab Med, 2017, 6:MO07-MO12, http://www.njlm.net/articles/PDF/2254/28472_CE(VSU)_F(AK)_PF1(VSU_GG)_PFA(VSU_GG)_PF2(VSU_GG).pdf
27. Mandal J, Ponnambath DK, Parija SC, Ethics of scientific publication, Trop Parasitol, 2016, 6(2):100-2, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048695/
28. Mandal J, Ponnambath DK, Parija SC, Utilitarian and deontological ethics in medicine, Trop Parasitol, 2016, 6(1):5-7, https://www.ncbi.nlm.nih.gov/pubmed/26998430
29. Dinoop KP, Parija SC, Mandal J, Swaminathan RP, Narayanan P., Comparison of nested-multiplex, Taqman & SYBR Green real-time PCR in diagnosis of amoebic liver abscess in a tertiary health care institute in India. Indian J Med Res 2016;143(1):49?56. (IF: 1.532), Indian J Med Res, 2016, 143(1):49-56., https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822369/
30. Mandal J, Dinoop KP, Parija SC, Microethics in medical education and practice, Trop Parasitol, 2015, 5(2):86-7, https://www.ncbi.nlm.nih.gov/pubmed/26629449
31. Mandal J, Dinoop KP, Parija SC, Ethics of international collaboration, Trop Parasitol, 2015, 5(1):6-8., https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326997/
32. Parija SC, Dinoop KP, Venugopal H, Diagnosis and management of human babesiosis, Trop Parasitol, 2015, 5(2):88-93., https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557163/
33. Parija SC, Dinoop KP, Venugopal H, Management of granulomatous amebic encephalitis., Trop Parasitol, 2015, 5(1):23-8., https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326989/
34. Mandal J, Ponnambath DK, Bhosale NK, Das A, Novel strain of Shigella dysenteriae serotype 7 from India, New Microbes New Infect, 2015, 7:97-9., https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552805/
35. Bhaskar M, Dinoop KP, Mandal J, Characterization of ceftriaxone-resistant Aeromonas spp. isolates from stool samples of both children and adults in Southern India, J Health Popul Nutr, 2015, 33(1):26, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025982/
36. Parija SC, Mandal J, Ponnambath DK, Laboratory methods of identification of Entamoeba histolytica and its differentiation from look-alike Entamoeba spp., Trop Parasitol, 2014, 4(2):90-5., https://www.ncbi.nlm.nih.gov/pubmed/25250228
37. Parija SC, Ponnambath DK, Laboratory diagnosis of Taenia asiatica in humans and animals., Trop Parasitol, 2013, 3(2):120-4., https://www.ncbi.nlm.nih.gov/pubmed/24470995
38. Mandal J, Dinoop KP, Parija SC, Increasing antimicrobial resistance of Vibrio cholerae OI biotype E1 tor strains isolated in a tertiary-care centre in India., J Health Popul Nutr, 2012, 30(1):12-6, https://www.ncbi.nlm.nih.gov/pubmed/22524114